SCHEMBL3799414

SCHEMBL3799414

C=C(C)C(=O)N(C[C]=O)C(=O)CN

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1521344 0.80 CHRM1 (0.39)
SCHEMBL6509835 0.76 GAA (0.31)
SCHEMBL14836211 0.76 GLRA1 (0.33) TDP1
SCHEMBL7746730 0.75
SCHEMBL29155241 0.71 CTSD (0.31)
SCHEMBL18322817 0.71
SCHEMBL8605865 0.71
SCHEMBL29155250 0.70 TDP1 (0.36) TDP1
SCHEMBL7747137 0.69 HDAC6 (0.36)
SCHEMBL582879 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10172962-B2 Macromolecular delivery systems for non-invasive imaging, evaluation and treatment of arthritis and other inflammatory diseases UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2019-01-08 US claimed
US-10092662-B2 Macromolecular delivery systems for non-invasive imaging, evaluation and treatment of arthritis and other inflammatory diseases UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2018-10-09 US claimed
US-20180207296-A1 Macromolecular Delivery Systems for Non-Invasive Imaging, Evaluation and Treatment of Arthritis and Other Inflammatory Diseases BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2018-07-26 US claimed
EP-3338816-A1 COMPOSITIONS AND METHODS FOR DETECTING AND TREATING IMPLANT LOOSENING AND OSTEOLYSIS Board Of Regents Of The University Of Nebraska (US) 2018-06-27 EP claimed
US-20210214389-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA, LLC 2021-07-15 US disclosed
EP-3843749-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME Osteoanalgesia, LLC (US) 2021-07-07 EP disclosed
WO-2020047231-A9 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA LLC (US) 2020-04-02 WO disclosed
WO-2020047231-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME OSTEOANALGESIA LLC (US) 2020-03-05 WO disclosed
EP-2210616-A1 Multifunctional stealth nanoparticles for biomedical use Centre National de la Recherche Scientifique (FR) 2010-07-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214389-A1 DIASTEREOMERIC CONJUGATE COMPOSITIONS AND METHODS OF MAKING AND USING SAME NR3C1, GCG, NR3C2 TDP1 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.