Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1330188 | 0.68 | ALDH1A1 (0.40) | ALDH1A1TP53GAAMAPTTSHR | |
| SCHEMBL1478593 | 0.67 | MAOB (0.31) | — | |
| Benzene SCHEMBL29259900 | 0.65 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL27569931 | 0.65 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL28384296 | 0.63 | TDP1 (0.30) | — | |
| SCHEMBL3799519 | 0.63 | NPC1 (0.32) | ALDH1A1TP53GAAMAPTTSHR | |
| SCHEMBL14721941 | 0.63 | KMT2A (0.46) | ALDH1A1TSHR | |
| SCHEMBL7938546 | 0.62 | NPSR1 (0.50) | ALDH1A1TP53TSHRSMN1; SMN2 | |
| SCHEMBL1040765 | 0.62 | PYCR1 (0.32) | — | |
| SCHEMBL688471 | 0.62 | ALDH1A1 (0.56) | ALDH1A1MAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139888-A2 | IMIDAZOÝ1,2-A¨PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008121687-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-10-09 | — | — | WO | disclosed |