Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.48 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799708 | 0.79 | GLA (0.53) | NPC1L3MBTL1GLATDP1HAO1 | |
| SCHEMBL11126196 | 0.79 | MAPT (0.55) | GLATDP1HAO1LMNAALDH1A1 | |
| SCHEMBL20244682 | 0.76 | MAPT (0.61) | NPC1L3MBTL1GLATDP1HAO1 | |
| SCHEMBL1620755 | 0.76 | MAPT (0.67) | NPC1L3MBTL1GLATDP1HAO1 | |
| SCHEMBL7060516 | 0.76 | MAPT (0.67) | NPC1L3MBTL1GLATDP1HAO1 | |
| SCHEMBL1620754 | 0.76 | MAPT (0.67) | NPC1L3MBTL1GLATDP1HAO1 | |
| SCHEMBL1034505 | 0.75 | MAPT (0.73) | NPC1L3MBTL1GLATDP1HAO1 | |
| SCHEMBL1034506 | 0.75 | MAPT (0.73) | NPC1L3MBTL1GLATDP1HAO1 | |
| SCHEMBL2153308 | 0.75 | MAPT (0.73) | NPC1L3MBTL1GLATDP1HAO1 | |
| SCHEMBL7659599 | 0.75 | GLA (0.57) | NPC1L3MBTL1GLATDP1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860213-A2 | Bioactive coating on surfaces | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-08-26 | — | — | EP | claimed |
| EP-0940674-A2 | Biosensor having a passivation layer | HÜLS AKTIENGESELLSCHAFT (DE) | 1999-09-08 | — | — | EP | disclosed |
| EP-0860213-A2 | Bioactive coating on surfaces | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-08-26 | — | — | EP | disclosed |
| EP-0852952-A2 | Bioactive coating of surfaces | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0814116-A1 | Hydrophilic coating of polymeric substrate surfaces | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-12-29 | — | — | EP | disclosed |