Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681959 | 0.97 | OPRL1 (0.44) | OPRL1OPRM1OPRK1C5AR1CYP2D6 | |
| SCHEMBL4800257 | 0.83 | OPRL1 (0.36) | OPRL1OPRM1OPRK1CYP2D6CYP3A4 | |
| SCHEMBL4675598 | 0.82 | CYP3A4 (0.40) | OPRL1OPRM1C5AR1CYP2D6CYP3A4 | |
| SCHEMBL4681962 | 0.81 | OPRL1 (0.46) | OPRL1OPRM1OPRK1C5AR1ENPP2 | |
| SCHEMBL4681961 | 0.81 | OPRL1 (0.46) | OPRL1OPRM1OPRK1C5AR1ENPP2 | |
| SCHEMBL3398375 | 0.80 | CACNA1G (0.35) | C5AR1CYP2D6CYP3A4CACNA1GCACNA1H | |
| SCHEMBL4734750 | 0.79 | DPP7 (0.37) | OPRL1OPRM1OPRK1CYP2D6CYP3A4 | |
| SCHEMBL3665332 | 0.79 | POLB (0.35) | OPRL1OPRM1OPRK1C5AR1CACNA1G | |
| SCHEMBL4804462 | 0.79 | CACNA1G (0.43) | OPRL1OPRM1OPRK1C5AR1CYP2D6 | |
| SCHEMBL3665336 | 0.78 | CHRM5 (0.36) | C5AR1CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155676-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | Commissariat à l'Energie Atomique (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |