Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 16/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681961 | 1.00 | OPRL1 (0.46) | OPRL1OPRM1OPRK1ENPP2C5AR1 | |
| SCHEMBL4675602 | 0.85 | CYP3A4 (0.41) | OPRL1OPRM1C5AR1CACNA1GCACNA1H | |
| SCHEMBL4681956 | 0.84 | OPRL1 (0.48) | OPRL1OPRM1OPRK1ENPP2C5AR1 | |
| SCHEMBL4681959 | 0.83 | OPRL1 (0.44) | OPRL1OPRM1OPRK1ENPP2C5AR1 | |
| SCHEMBL4674540 | 0.82 | HTR4 (0.36) | OPRL1OPRM1OPRK1C5AR1OPRD1 | |
| SCHEMBL4674544 | 0.82 | HTR4 (0.36) | OPRL1OPRM1OPRK1C5AR1OPRD1 | |
| SCHEMBL4804471 | 0.81 | CACNA1G (0.43) | OPRL1OPRM1OPRK1C5AR1OPRD1 | |
| SCHEMBL4804476 | 0.81 | CACNA1G (0.43) | OPRL1OPRM1OPRK1C5AR1OPRD1 | |
| SCHEMBL3799851 | 0.81 | OPRL1 (0.42) | OPRL1OPRM1OPRK1ENPP2C5AR1 | |
| SCHEMBL3748474 | 0.80 | OPRL1 (0.48) | OPRL1OPRM1OPRK1ENPP2C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |