Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | BLK | P51451 | 2/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675598 | 0.83 | CYP3A4 (0.40) | DPP7CACNA1GCACNA1HDRD2DRD4 | |
| SCHEMBL4681959 | 0.82 | OPRL1 (0.44) | CACNA1GCACNA1HOPRL1OPRM1OPRD1 | |
| SCHEMBL3398375 | 0.81 | CACNA1G (0.35) | DPP7CACNA1GCACNA1HDPP8DPP9 | |
| SCHEMBL3665332 | 0.80 | POLB (0.35) | DPP7CACNA1GCACNA1HOPRL1OPRM1 | |
| SCHEMBL3799851 | 0.79 | OPRL1 (0.42) | CACNA1GCACNA1HOPRL1OPRM1OPRK1 | |
| SCHEMBL3665336 | 0.79 | CHRM5 (0.36) | DPP7CACNA1GCACNA1HDPP8DPP9 | |
| SCHEMBL4730149 | 0.79 | HSD11B1 (0.41) | CACNA1GCACNA1HDRD2DRD4DRD3 | |
| SCHEMBL3808537 | 0.77 | CACNA1G (0.34) | CACNA1GCACNA1HDRD2CYP3A4CYP2D6 | |
| SCHEMBL1835272 | 0.77 | OPRM1 (0.50) | DRD2DRD4DRD3OPRL1OPRM1 | |
| SCHEMBL4676164 | 0.77 | HSD11B1 (0.44) | MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |