Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9228837 | 0.80 | HTR1A (0.34) | PTGS1PTGS2 | |
| SCHEMBL181056 | 0.78 | HTR1A (0.37) | MAPK1 | |
| SCHEMBL5664409 | 0.78 | HTR1A (0.37) | MAPK1 | |
| SCHEMBL45794 | 0.75 | PTGS1 (0.33) | PTGS1PTGS2PTGER3PTGER2 | |
| SCHEMBL6849179 | 0.74 | PTGS1 (0.47) | PTGS1PTGS2MAPK1 | |
| SCHEMBL14348230 | 0.71 | CPB2 (0.33) | — | |
| Tert-Butyl Formate SCHEMBL28048328 | 0.70 | HTR1A (0.34) | — | |
| SCHEMBL6417719 | 0.69 | — | — | |
| SCHEMBL960938 | 0.68 | PTGS1 (0.40) | PTGS1PTGS2PTGER3PTGER2PTGER4 | |
| Succinic Acid SCHEMBL23234379 | 0.66 | PTGS1 (0.42) | PTGS1PTGS2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250498-A1 | DRUG SELECTION FOR BREAST CANCER THERAPY USING ANTIBODY-BASED ARRAYS | Prometheus Laboratories Inc. (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009108637-A1 | DRUG SELECTION FOR BREAST CANCER THERAPY USING ANTIBODY-BASED ARRAYS | PROMETHEUS LABORATORIES, INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009012288-A2 | TRIFUNCTIONAL IMAGING AGENT FOR MONOCLONAL ANTIBODY TUMOR-TARGETED IMAGING | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-01-22 | — | — | WO | disclosed |