SCHEMBL45794

SCHEMBL45794

NCCCCCC(=O)OC(=O)O.O=C1C=CC(=O)N1CC1CCC(N2C(=O)CCC2=O)CC1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 4/20 0.33
PTGS2 P35354 4/20 0.33
PTGER3 P43115 1/20 0.30
PTGER2 P43116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1766181 0.86 PTGS1 (0.36) PTGS1PTGS2
SCHEMBL6417719 0.85
SCHEMBL861358 0.84 KMT2A (0.31) PTGER2
SCHEMBL14348230 0.82 CPB2 (0.33)
SCHEMBL20661164 0.81 PTGS1 (0.35) PTGS1PTGS2
Bicarbonate SCHEMBL9228837 0.80 HTR1A (0.34) PTGS1PTGS2
SCHEMBL5664409 0.78 HTR1A (0.37)
SCHEMBL181056 0.78 HTR1A (0.37)
SCHEMBL19326880 0.75 PTGS1 (0.32) PTGS1PTGS2
SCHEMBL3800428 0.75 PTGS1 (0.40) PTGS1PTGS2PTGER3PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1821 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238432-A1 METHOD FOR GLYCOPROTEIN MODIFICATION HONEYBEAR BIOSCIENCES INC. (TW) 2024-07-18 US claimed
WO-2024145600-A1 METHOD FOR GLYCOPROTEIN MODIFICATION HONEYBEAR BIOSCIENCES INC. (TW) 2024-07-04 WO claimed
US-11944688-B2 Biologically active compounds SUTURA THERAPEUTICS LTD (GB) 2024-04-02 US claimed
WO-2023220678-A1 CROSS-LINKED TUMOR LYSATE SPHERICAL NUCLEIC ACIDS AS CANCER VACCINES NORTHWESTERN UNIVERSITY (US) 2023-11-16 WO claimed
US-11725222-B2 Cleavable nucleotide analogs and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-08-15 US claimed
WO-2023146293-A1 IMMUNOCONJUGATE TARGETING C-KIT 주식회사 노벨티노빌리티 2023-08-03 WO claimed
US-20230158166-A1 BIOLOGICALLY ACTIVE COMPOUNDS SUTURA THERAPEUTICS LTD (GB) 2023-05-25 US claimed
EP-4143316-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2023-03-08 EP claimed
US-11541124-B2 Biologically active compound conjugated to a stapled or stitched peptide SUTURA THERAPEUTICS LTD (TC) 2023-01-03 US claimed
EP-4103585-A1 PEPTIDES TARGETING MACROPHAGES, AND CONJUGATES, COMPOSITIONS, AND USES THEREOF Twinpig Biolab, Inc. (KR) 2022-12-21 EP claimed
EP-1525480-A1 MULTIPLE HYBRID IMMUNOASSAY I-STAT CORPORATION (US) 2005-04-27 EP claimed
US-20040072743-A1 Pharmaceutical composition of modified pna molecules PANTHECO A/S (DK) 2004-04-15 US claimed
WO-2004011947-A1 MULTIPLE HYBRID IMMUNOASSAY I-STAT CORPORATION (US) 2004-02-05 WO claimed
US-20040018577-A1 Multiple hybrid immunoassay ABBOTT POINT OF CARE INC. 2004-01-29 US claimed
US-20030129642-A1 Novel compositions and methods for inhibiting light-induced inactivation of biological reagents BIOSITE DIAGNOSTICS, INC. 2003-07-10 US claimed
US-6544797-B1 Oxidation resistance; complexing BIOSITE DIAGNOSTICS, INC. 2003-04-08 US claimed
EP-1296718-A1 PHARMACEUTICAL COMPOSITION OF MODIFIED PNA MOLECULES Pantheco A/S (DK) 2003-04-02 EP claimed
WO-2001076636-A2 PHARMACEUTICAL COMPOSITION OF MODIFIED PNA MOLECULES PANTHECO A/S (DK) 2001-10-18 WO claimed
EP-0972194-A2 COMPOSITIONS AND METHODS FOR INHIBITING LIGHT-INDUCED INACTIVATION OF BIOLOGICAL REAGENTS BIOSITE DIAGNOSTICS INC. (US) 2000-01-19 EP claimed
WO-1998045705-A2 COMPOSITIONS AND METHODS FOR INHIBITING LIGHT-INDUCED INACTIVATION OF BIOLOGICAL REAGENTS BIOSITE DIAGNOSTICS INCORPORATED (US) 1998-10-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11541124-B2 Biologically active compound conjugated to a stapled or stitched peptide BPGM, TMPO, SLC7A1 PTGS1 4511/4885PTGS2 4428/4885PTGER3 4437/4885
US-11944688-B2 Biologically active compounds BPGM, PICALM, TMPO PTGS1 4574/4885PTGS2 4400/4885PTGER3 4395/4885
US-20240238432-A1 METHOD FOR GLYCOPROTEIN MODIFICATION SIGLEC7, FUT5, FUT6 PTGS1 3702/4885PTGS2 3230/4885PTGER3 4215/4885
US-20230158166-A1 BIOLOGICALLY ACTIVE COMPOUNDS BPGM, PICALM, TMPO PTGS1 4574/4885PTGS2 4400/4885PTGER3 4395/4885
US-11725222-B2 Cleavable nucleotide analogs and uses thereof TYMP, DUT, NT5C3B PTGS1 1127/4885PTGS2 1270/4885PTGER3 2264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.