Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904000 | 0.86 | GGPS1 (0.47) | AKR1C3AKR1C4AKR1C2GGPS1HTT | |
| SCHEMBL13105380 | 0.84 | FOLH1 (0.56) | HTTFOLH1 | |
| SCHEMBL8848832 | 0.78 | TAAR1 (0.47) | AKR1C3AKR1C2GGPS1ALDH1A1 | |
| SCHEMBL2811400 | 0.78 | PRSS1 (0.44) | AKR1C3AKR1C2GGPS1PRSS1PRSS2 | |
| SCHEMBL27314752 | 0.78 | GGPS1 (0.43) | AKR1C3AKR1C4AKR1C2GGPS1HTT | |
| SCHEMBL2229094 | 0.77 | MAOB (0.47) | AKR1C3AKR1C2GGPS1PRSS1PRSS2 | |
| SCHEMBL13189961 | 0.77 | GGPS1 (0.42) | AKR1C3AKR1C4AKR1C2GGPS1HTT | |
| SCHEMBL27259071 | 0.77 | TAAR1 (0.46) | — | |
| SCHEMBL28041732 | 0.77 | CYP1A2 (0.44) | AKR1C3AKR1C2GGPS1HTTHPGD | |
| SCHEMBL9454043 | 0.77 | GGPS1 (0.42) | AKR1C3AKR1C4AKR1C2GGPS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454326-B1 | Dispersant-antioxidant multifunctional viscosity index improver | TEXACO DEVELOPMENT CORP (US) | 1996-02-28 | — | — | EP | claimed |
| US-4769419-A | ACRYLATED CONJUGATED POLYMERS REACTED WITH ISOCYANATES | LORD CORPORATION, A CORP OF PA. | 1988-09-06 | — | — | US | claimed |
| WO-2010065329-A2 | NANOPARTICLES FOR CANCER TREATMENT | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2010-06-10 | — | — | WO | disclosed |
| US-20060241178-A1 | Compositions and methods for treating lung cancer | IMMUNEGUARD LLC (US) | 2006-10-26 | — | — | US | disclosed |
| WO-2004060365-A1 | COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER | AMERICAN HEALTH FOUNDATION (US) | 2004-07-22 | — | — | WO | disclosed |