Sulfuric Acid

Sulfuric Acid

SCHEMBL3800616

COc1cc(Oc2ccc(Oc3cccc(C)c3)cc2)c(OC)cc1[N+]#N.O=S(=O)(O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
HTT P42858 1/20 0.48
ALDH1A1 P00352 3/20 0.43
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
ACHE P22303 1/20 0.40
MAPT P10636 1/20 0.39
GAA P10253 2/20 0.39
PGR P06401 3/20 0.38
MAPK1 P28482 1/20 0.38
GFER P55789 1/20 0.38
MRGPRX1 Q96LB2 1/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL3800618 0.95 HTT (0.49) ARTDP1L3MBTL1HTTALDH1A1
Sulfuric Acid SCHEMBL3800614 0.93 HTT (0.51) ARTDP1L3MBTL1HTTALDH1A1
Hydrochloric Acid SCHEMBL11745983 0.91 AR (0.53) ARTDP1L3MBTL1HTTALDH1A1
SCHEMBL8083005 0.77 TTR (0.49) ARL3MBTL1HTTALDH1A1MAPK1
Nitrogen SCHEMBL11745998 0.72 AR (0.59) ARTDP1L3MBTL1HTTALDH1A1
SCHEMBL31448149 0.71 ALDH1A1 (0.61) ARTDP1L3MBTL1HTTALDH1A1
SCHEMBL3294529 0.70 ACHE (0.72) ARTDP1L3MBTL1HTTALDH1A1
SCHEMBL30358265 0.70 ACHE (0.72) ARTDP1L3MBTL1HTTALDH1A1
SCHEMBL14159539 0.70 ALDH1A1 (0.80) ARTDP1L3MBTL1HTTALDH1A1
SCHEMBL10013917 0.70 ALDH1A1 (0.80) ARTDP1L3MBTL1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1656551-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR Honeywell International Inc. (US) 2006-05-17 EP claimed
WO-2005019816-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR HONEYWELL INTERNATIONAL, INC. (US) 2005-03-03 WO claimed
US-20050042758-A1 Leak detection method using microencapsulated dye precursor HONEYWELL CORPORATION 2005-02-24 US claimed
US-8703092-B2 Type separation of single-walled carbon nanotubes via two-phase liquid extraction UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2014-04-22 US disclosed
US-20100166637-A1 Type Separation of Single-Walled Carbon Nanotubes via Two-Phase Liquid Extraction UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2010-07-01 US disclosed
WO-2008057070-A2 TYPE SEPARATION OF SINGLE-WALLED CARBON NANOTUBES VIA PHASE TRANSFER UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-05-15 WO disclosed
EP-1421447-A4 IMAGEABLE COMPOSITION CONTAINING INFRARED ABSORBER WITH COUNTER ANION DERIVED FROM A NON-VOLATILE ACID KODAK POLYCHROME GRAPHICS LLC (US) 2006-09-06 EP disclosed
US-7056639-B2 Imageable composition containing an infrared absorber with counter anion derived from a non-volatile acid EASTMAN KODAK COMPANY (US) 2006-06-06 US disclosed
EP-1656551-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR Honeywell International Inc. (US) 2006-05-17 EP disclosed
US-6921620-B2 Acid curable composition of an acid generator; an infrared absorber; and optional colorant KODAK POLYCHROME GRAPHICS LLC (US) 2005-07-26 US disclosed
US-20050079439-A1 Imageable composition containing an infrared absorber with counter anion derived from a non-volatile acid KODAK POLYCHROME GRAPHICS LLC (US) 2005-04-14 US disclosed
US-6638679-B2 Photosensitive compositions having mixtures of alkoxy and non-alkoxy diazonium salt containing compounds KODAK POLYCHROME GRAPHICS, LLC 2003-10-28 US disclosed
US-20030194635-A1 Isocyanate crosslinked imageable compositions KODAK POLYCHROME GRAPHICS, L.L.C. 2003-10-16 US disclosed
US-20030129526-A1 Containing acid curable polymer, acid generator and infrared radiation absorberr KODAK POLYCHROME GRAPHICS, L.L.C. 2003-07-10 US disclosed
US-20030113655-A1 Acid curable composition of an acid generator; an infrared absorber; and optional colorant KODAK POLYCHROME GRAPHICS, L.L.C 2003-06-19 US disclosed
US-20030082474-A1 Printing plate patterns; mixture of acid, acid generator and acid curable compound KODAK POLYCHROME GRAPHICS, L.L.C 2003-05-01 US disclosed
WO-2003019293-A1 NEGATIVE WORKING IMAGEABLE COMPOSITION CONTAINING SULFONIC ACID KODAK POLYCHROME GRAPHICS, L.L.C. (US) 2003-03-06 WO disclosed
WO-2003019294-A1 IMAGEABLE COMPOSITION CONTAINING INFRARED ABSORBER WITH COUNTER ANION DERIVED FROM A NON-VOLATILE ACID KODAK POLYCHROME GRAPHICS, L.L.C. (US) 2003-03-06 WO disclosed
WO-2003007076-A2 PHOTOSENSITIVE COMPOSITIONS HAVING MIXTURES OF ALKOXY AND NON-ALKOXY DIAZONIUM SALT CONTAINING COMPOUNDS KODAC POLYCHROME GRAPHICS, L.L.C. (US) 2003-01-23 WO disclosed
US-20030013035-A1 Photosensitive compositions having mixtures of alkoxy and non-alkoxy diazonium salt containing compounds KODAK POLYCHROME GRAPHICS, L.L.C. 2003-01-16 US disclosed