Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 9/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP7 | P09237 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1054689 | 0.87 | F2R (0.37) | F2RLMNAALDH1A1IDO1TRPC6 | |
| SCHEMBL3794078 | 0.86 | F2R (0.45) | F2RACACBLMNAALDH1A1IDO1 | |
| SCHEMBL1056811 | 0.82 | ALDH1A1 (0.35) | F2RLMNAALDH1A1CNR1TMEM97 | |
| SCHEMBL3723216 | 0.79 | F2R (0.36) | F2RACACBLMNAALDH1A1IDO1 | |
| SCHEMBL3723797 | 0.78 | F2R (0.35) | F2RACACBLMNAALDH1A1IDO1 | |
| SCHEMBL3764088 | 0.75 | F2R (0.60) | F2RCNR1TMEM97MEN1KMT2A | |
| SCHEMBL1054200 | 0.74 | F2R (0.46) | F2RALDH1A1CNR1TMEM97MEN1 | |
| SCHEMBL1581027 | 0.74 | F2R (0.56) | F2RCNR1TMEM97 | |
| SCHEMBL485798 | 0.74 | F2R (0.62) | F2RKMT2A | |
| SCHEMBL10278942 | 0.73 | F2R (0.43) | F2RLMNAALDH1A1IDO1TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136138-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136144-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |