Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723216 | 0.82 | F2R (0.36) | F2RACACBDPP4DPP7PREP | |
| SCHEMBL3794078 | 0.78 | F2R (0.45) | F2RACACBLMNAALDH1A1IDO1 | |
| SCHEMBL3800964 | 0.78 | F2R (0.41) | F2RACACBLMNAALDH1A1IDO1 | |
| SCHEMBL3722789 | 0.74 | F2R (0.35) | F2RACACBALDH1A1 | |
| SCHEMBL3732951 | 0.68 | F2R (0.44) | F2RDPP4DPP7HRH3SLC6A3 | |
| SCHEMBL3727927 | 0.68 | CHRNB2 (0.42) | ALDH1A1IDO1 | |
| SCHEMBL10278942 | 0.68 | F2R (0.43) | F2RLMNAALDH1A1IDO1 | |
| SCHEMBL1581027 | 0.67 | F2R (0.56) | F2R | |
| SCHEMBL10278542 | 0.67 | LMNA (0.39) | F2RLMNAALDH1A1IDO1SLC6A4 | |
| SCHEMBL485798 | 0.67 | F2R (0.62) | F2RMCHR1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136144-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |