Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11768323 | 1.00 | LMNA (0.31) | LMNAMAPTHTTFDPS | |
| SCHEMBL11767128 | 1.00 | LMNA (0.31) | LMNAMAPTHTTFDPS | |
| SCHEMBL5694538 | 0.75 | CYP2D6 (0.35) | — | |
| SCHEMBL10662577 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL1120453 | 0.74 | LMNA (0.45) | LMNAMAPTHTTFDPS | |
| SCHEMBL229258 | 0.74 | LMNA (0.45) | LMNAMAPTHTTFDPS | |
| SCHEMBL22412645 | 0.74 | LMNA (0.45) | LMNAMAPTHTTFDPS | |
| SCHEMBL11859960 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL2704379 | 0.72 | FDPS (0.33) | FDPS | |
| SCHEMBL45551 | 0.72 | FDPS (0.33) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8747810-B2 | Compositions and methods for imaging tissues, organs and tumors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120269724-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-10-25 | — | — | US | disclosed |
| WO-2010144891-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269724-A1 | COMPOSITIONS AND METHODS FOR IMAGING TISSUES, ORGANS AND TUMORS | SSTR3, TACR1, SSTR5 | LMNA 4716/4885MAPT 3819/4885HTT 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.