Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | PTPRB | P23467 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431853 | 0.81 | ALDH1A1 (0.57) | ALDH1A1RECQLMMP8PTPRBPTPN1 | |
| SCHEMBL3987534 | 0.79 | ESR1 (0.49) | BLMALDH1A1RECQLMMP8ESR1 | |
| SCHEMBL24835573 | 0.79 | PTPRB (0.42) | ALDH1A1RECQLMMP8PTPRBPTPN1 | |
| SCHEMBL3801917 | 0.78 | ESR1 (0.47) | BLMESR1ESR2CA12CA1 | |
| SCHEMBL8486868 | 0.76 | ESR1 (0.50) | BLMALDH1A1RECQLMMP8ESR1 | |
| SCHEMBL3920792 | 0.75 | ESR1 (0.47) | BLMALDH1A1RECQLMMP8ESR1 | |
| SCHEMBL13792083 | 0.75 | ESR1 (0.48) | BLMALDH1A1RECQLMMP8ESR1 | |
| SCHEMBL3993833 | 0.75 | ESR1 (0.48) | BLMALDH1A1RECQLMMP8ESR1 | |
| SCHEMBL9386398 | 0.74 | BLM (0.63) | BLMALDH1A1RECQLMMP8ESR1 | |
| SCHEMBL9386400 | 0.74 | BLM (0.63) | BLMALDH1A1RECQLMMP8ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064545-B1 | METHOD FOR IDENTIFYING COMPOUNDS THAT ACT AS INSULIN-SENSITIZERS | PIRAMAL LIFE SCIENCES LTD (IN) | 2012-07-04 | — | — | EP | disclosed |
| EP-2256496-A2 | Method for identifying compounds that act as insulin-sensitizers | Piramal Life Sciences Limited (IN) | 2010-12-01 | — | — | EP | disclosed |
| US-20090318465-A1 | METHOD FOR IDENTIFYING COMPOUNDS THAT ACT AS INSULIN-SENSITIZERS | Piramal Enterprises Limited (IN) | 2009-12-24 | — | — | US | disclosed |
| EP-2064545-A2 | METHOD FOR IDENTIFYING COMPOUNDS THAT ACT AS INSULIN-SENSITIZERS | Piramal Life Sciences Limited (IN) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008035309-A2 | METHOD FOR IDENTIFYING COMPOUNDS THAT ACT AS INSULIN-SENSITIZERS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318465-A1 | METHOD FOR IDENTIFYING COMPOUNDS THAT ACT AS INSULIN-SENSITIZERS | GPR119, SLC2A4, INSR | BLM 4214/4885ALDH1A1 1184/4885RECQL 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.