SCHEMBL380200

SCHEMBL380200

CCCCC(O)(CCC)CCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.48
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 7/20 0.46
PPARD Q03181 7/20 0.46
PPARA Q07869 7/20 0.46
HDAC11 Q96DB2 5/20 0.46
TSHR P16473 4/20 0.46
PTPN1 P18031 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
MEN1 O00255 1/20 0.46
ESR1 P03372 1/20 0.46
ALOX15 P16050 1/20 0.46
PDE4A P27815 1/20 0.46
KMT2A Q03164 1/20 0.46
PDE3A Q14432 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380275 0.96 AKR1B1 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL380564 0.92 AKR1B1 (0.48) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL380948 0.91 FFAR3 (0.50) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL23111353 0.89 AKR1B1 (0.42) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL1946680 0.87 AKR1B1 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL381782 0.85 ALDH1A1 (0.48) AKR1B1GPR84PPARGPPARDPPARA
Adipic Acid SCHEMBL28739491 0.84 GPR84 (0.65) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL2349317 0.82 FDPS (0.37) TSHRALDH1A1ESR1
SCHEMBL2350621 0.82 FDPS (0.37) TSHRALDH1A1ESR1
SCHEMBL380088 0.81 AKR1B1 (0.50) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3793973-B1 PROCESS FOR PRODUCING AN INTRAMOLECULAR DIESTER OF A HYDROXYCARBOXYLIC ACID AND PROCESS FOR PRODUCING A POLYHYDROXYCARBOXYLIC ACID. FRAUNHOFER GES FORSCHUNG (DE) 2022-12-28 EP claimed
EP-3793973-A1 PROCESS FOR PRODUCING AN INTRAMOLECULAR DIESTER OF A HYDROXYCARBOXYLIC ACID AND PROCESS FOR PRODUCING A POLYHYDROXYCARBOXYLIC ACID. FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. (DE) 2021-03-24 EP claimed
WO-2009127009-A1 CONDENSATION POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2009-10-22 WO claimed
EP-3793973-B1 PROCESS FOR PRODUCING AN INTRAMOLECULAR DIESTER OF A HYDROXYCARBOXYLIC ACID AND PROCESS FOR PRODUCING A POLYHYDROXYCARBOXYLIC ACID. FRAUNHOFER GES FORSCHUNG (DE) 2022-12-28 EP disclosed
US-20210139390-A1 PRODUCTION METHOD OF ORGANIC COMPOUND UNITIKA LTD. (JP) 2021-05-13 US disclosed
EP-3793973-A1 PROCESS FOR PRODUCING AN INTRAMOLECULAR DIESTER OF A HYDROXYCARBOXYLIC ACID AND PROCESS FOR PRODUCING A POLYHYDROXYCARBOXYLIC ACID. FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. (DE) 2021-03-24 EP disclosed
CN-112384489-A Method for producing organic compound 尤尼吉可株式会社 2021-02-19 CN disclosed
WO-2020009016-A1 METHOD FOR PRODUCING ORGANIC COMPOUND ユニチカ株式会社 2020-01-09 WO disclosed
CN-105121504-B The process for purification of aliphatic polyester and the aliphatic polyester refined with this method 株式会社武藏野化学研究所 2018-05-01 CN disclosed
US-9688809-B2 Method for purifying aliphatic polyester and aliphatic polyester purified with said method MUSASHINO CHEMICAL LABORATORY, LTD. (JP) 2017-06-27 US disclosed
US-20160083507-A1 METHOD FOR PURIFYING ALIPHATIC POLYESTER AND ALIPHATIC POLYESTER PURIFIED WITH SAID METHOD MUSASHINO CHEMICAL LABORATORY, LTD. (JP) 2016-03-24 US disclosed
US-5616783-A DISSOLVING IN WATER IMMISCIBLE PHENOL-TYPE COMPOUND, CONTACTING WITH WATER CONTAINING ACIDIC MATERIAL, SEPARATING AND ISOLATING MITSUI TOATSU CHEMICALS, INC. (JP) 1997-04-01 US disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed
US-5512653-A Lactic acid containing hydroxycarboxylic acid for the preparation of polhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1996-04-30 US disclosed
EP-0707024-A2 Purification process of polyhydroxycarboxylic acids MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-04-17 EP disclosed
US-5444143-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1995-08-22 US disclosed
US-5440008-A Condensation polymerization of hydroxycarboxylic acids in vertical reactor with ribbon stirrer, having flow pattern along walls in opposite direction to flow along axis of stirrer MITSUI TOATSU CHEMICALS, INC. (JP) 1995-08-08 US disclosed
US-5386004-A Contacting with acid substance in presence of organic solvent MITSUI TOATSU CHEMICALS, INC. (JP) 1995-01-31 US disclosed
EP-0603889-A2 Process for the preparation of lactic acid polyesters MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-29 EP disclosed
EP-0591978-A2 Polyhydroxycarboxylic acid and purification process thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-04-13 EP disclosed