Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | PI4KA | P42356 | 3/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6577280 | 0.87 | CYP1A2 (0.36) | TSHRAHCYNUDT1PI4KAPI4K2B | |
| SCHEMBL14779867 | 0.78 | TSHR (0.64) | TSHRRECQLAHCYNUDT1PI4KA | |
| SCHEMBL14779864 | 0.78 | TSHR (0.64) | TSHRRECQLAHCYNUDT1PI4KA | |
| SCHEMBL2025481 | 0.70 | CDK2 (0.47) | TSHRRECQL | |
| SCHEMBL6141622 | 0.70 | PI4KA (0.35) | TSHRNUDT1PI4KAPI4K2BPI4K2A | |
| SCHEMBL5667619 | 0.69 | ADORA2A (0.43) | TSHRNUDT1PI4KAPI4K2BPI4K2A | |
| SCHEMBL4455866 | 0.69 | PI4KA (0.38) | NUDT1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL14780258 | 0.68 | CDK2 (0.61) | TSHRRECQLNUDT1PI4KAPI4K2B | |
| SCHEMBL14779863 | 0.67 | TSHR (0.56) | TSHRRECQLAHCY | |
| SCHEMBL108321 | 0.66 | LTB4R (0.55) | PI4KAPI4K2BPI4K2API4KBPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9063122-B2 | Biomodulators for treatment or prevention of disease | GALLEGOS ALFREDO (MX) | 2015-06-23 | — | — | US | disclosed |
| US-20100130421-A1 | BIOMODULATORS FOR TREATMENT OR PREVENTION OF DISEASE | GALLEGOS ALFREDO | 2010-05-27 | — | — | US | disclosed |