SCHEMBL3803109

SCHEMBL3803109

CCCCCCCCCCCCCCCCCC(=O)O[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 1.00
▸ LMNA P02545 5/20 1.00
▸ AR P10275 3/20 0.62
▸ SERPINA6 P08185 2/20 0.60
▸ ALDH1A1 P00352 2/20 0.60
▸ SLC22A1 O15245 1/20 0.60
▸ SHBG P04278 1/20 0.60
▸ THRB P10828 1/20 0.60
▸ MCL1 Q07820 1/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ HIF1A Q16665 1/20 0.56
▸ HSD17B10 Q99714 1/20 0.56
▸ PGR P06401 3/20 0.53
▸ CYP3A4 P08684 3/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ ESR1 P03372 1/20 0.53
▸ POLB P06746 1/20 0.53
▸ ADORA3 P0DMS8 1/20 0.53
▸ CHRM1 P11229 1/20 0.53
▸ TBXA2R P21731 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nandrolone Decanoate SCHEMBL6151508 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
Nandrolone Decanoate SCHEMBL19834508 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
SCHEMBL635908 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
SCHEMBL11593159 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
SCHEMBL14568852 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
Nandrolone Decanoate SCHEMBL16107220 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
SCHEMBL11351978 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
Nandrolone Decanoate SCHEMBL10710160 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
SCHEMBL3850364 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1
Nandrolone Decanoate SCHEMBL30692744 1.00 MAPT (1.00) MAPTLMNAARSERPINA6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9592243-B2 Medical devices and methods comprising an anabolic agent for treatment of an injury WARSAW ORTHOPEDIC, INC. (US) 2017-03-14 — — US claimed
WO-2012148570-A1 MEDICAL DEVICES AND METHODS COMPRISING AN ANABOLIC AGENT FOR WOUND HEALING WARSAW ORTHOPEDIC, INC. (US) 2012-11-01 — — WO claimed
US-20120271275-A1 MEDICAL DEVICES AND METHODS COMPRISING AN ANABOLIC AGENT FOR WOUND HEALING WARSAW ORTHOPEDIC, INC. (US) 2012-10-25 — — US claimed
EP-1594462-B1 SURGICAL IMPLANT COMPPRISING AN ANABOLIC AND A CORTICOSTEROID JOHNSON & JOHNSON MEDICAL (DE) 2012-06-06 — — EP claimed
US-7829110-B2 Surgical implant comprising an anabolic and a corticosteroid ETHICON, INC. (US) 2010-11-09 — — US claimed
US-20060147488-A1 Surgical implant comprising an anabolic and a corticosteroid ETHICON, INC. 2006-07-06 — — US claimed
EP-1594462-A1 SURGICAL IMPLANT COMPPRISING AN ANABOLIC AND A CORTICOSTEROID Ethicon GmbH (DE) 2005-11-16 — — EP claimed
WO-2004071485-A1 SURGICAL IMPLANT COMPPRISING AN ANABOLIC AND A CORTICOSTEROID ETHICON GMBH (DE) 2004-08-26 — — WO claimed
WO-2004071547-A1 BONE FILLING MATERIAL COMPRISING ANABOLIC STEROID ETHICON GMBH (DE) 2004-08-26 — — WO claimed
US-9592243-B2 Medical devices and methods comprising an anabolic agent for treatment of an injury WARSAW ORTHOPEDIC, INC. (US) 2017-03-14 — — US disclosed
US-9511077-B2 Medical devices and methods comprising an anabolic agent for wound healing WARSAW ORTHOPEDIC, INC. (US) 2016-12-06 — — US disclosed
WO-2012148570-A1 MEDICAL DEVICES AND METHODS COMPRISING AN ANABOLIC AGENT FOR WOUND HEALING WARSAW ORTHOPEDIC, INC. (US) 2012-11-01 — — WO disclosed
US-20120271275-A1 MEDICAL DEVICES AND METHODS COMPRISING AN ANABOLIC AGENT FOR WOUND HEALING WARSAW ORTHOPEDIC, INC. (US) 2012-10-25 — — US disclosed
EP-1594462-B1 SURGICAL IMPLANT COMPPRISING AN ANABOLIC AND A CORTICOSTEROID JOHNSON & JOHNSON MEDICAL (DE) 2012-06-06 — — EP disclosed
US-7829110-B2 Surgical implant comprising an anabolic and a corticosteroid ETHICON, INC. (US) 2010-11-09 — — US disclosed
US-20060147488-A1 Surgical implant comprising an anabolic and a corticosteroid ETHICON, INC. 2006-07-06 — — US disclosed
EP-1594462-A1 SURGICAL IMPLANT COMPPRISING AN ANABOLIC AND A CORTICOSTEROID Ethicon GmbH (DE) 2005-11-16 — — EP disclosed
WO-2004071485-A1 SURGICAL IMPLANT COMPPRISING AN ANABOLIC AND A CORTICOSTEROID ETHICON GMBH (DE) 2004-08-26 — — WO disclosed
WO-2004071547-A1 BONE FILLING MATERIAL COMPRISING ANABOLIC STEROID ETHICON GMBH (DE) 2004-08-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120271275-A1 MEDICAL DEVICES AND METHODS COMPRISING AN ANABOLIC AGENT FOR WOUND HEALING AREG, FGF1, BMP2 MAPT 4816/4885LMNA 1969/4885AR 1245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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