SCHEMBL380430

SCHEMBL380430

COC([SiH3])(CCCN(C)C)OC

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
DNM1 Q05193 3/20 0.33
BCL2 P10415 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380031 0.93 ALDH1A1 (0.43) ALDH1A1TSHRDNM1
SCHEMBL379301 0.85 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL7911596 0.84 TDP1 (0.47) ALDH1A1TSHR
SCHEMBL379298 0.77 SIGMAR1 (0.33) ALDH1A1
SCHEMBL329401 0.77 ALDH1A1 (0.36) ALDH1A1TSHRDNM1BCL2
SCHEMBL12802099 0.76
SCHEMBL329698 0.75
SCHEMBL28331478 0.75 CA12 (0.30)
SCHEMBL8466926 0.73
SCHEMBL3655924 0.72 TSHR (0.32) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3912832-B2 RUBBER COMPOSITION AND TIRE SUMITOMO RUBBER IND (JP) 2026-04-29 EP disclosed
EP-4662253-A2 METHOD FOR PREPARING MONOMODAL POLYISOPRENE WITH DILITHIUM INITIATORS BRIDGESTONE CORPORATION (JP) 2025-12-17 EP disclosed
EP-4646450-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2025-11-12 EP disclosed
US-20250236693-A1 RESIN COMPOSITION, AND MOLDED PRODUCT, CURED PRODUCT, FILM, COMPOSITE MATERIAL, CURED COMPOSITE MATERIAL, LAMINATE, METAL FOIL WITH RESIN, AND VARNISH FOR CIRCUIT BOARD MATERIAL OBTAINEDTHEREFROM NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2025-07-24 US disclosed
US-20250179221-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-06-05 US disclosed
US-20250109282-A1 NATURAL RUBBER COMPOSITIONS FOR PNEUMATIC TIRES BRIDGESTONE CORPORATION (JP) 2025-04-03 US disclosed
US-12173098-B2 Modified vinylaromatic copolymer, production method therefor, modified conjugated diene copolymer obtained therefrom and composition thereof, crosslinked rubber object, and tire member NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-12-24 US disclosed
EP-4442713-A1 MODIFIED VINYL AROMATIC COPOLYMER, METHOD FOR PRODUCING SAME, MODIFIED CONJUGATED DIENE COPOLYMER OBTAINED FROM SAME, RESIN COMPOSITION, CROSSLINKED RESIN AND STRUCTURAL MEMBER NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-10-09 EP disclosed
WO-2024168332-A2 METHOD FOR PREPARING MONOMODAL POLYISOPRENE WITH DILITHIUM INITIATORS BRIDGESTONE CORPORATION (JP) 2024-08-15 WO disclosed
WO-2024148082-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2024-07-11 WO disclosed
EP-2174801-A2 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2010-04-14 EP disclosed
US-20100084065-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2010-04-08 US disclosed
EP-0270071-B1 Process for preparing modified diene polymer rubbers SUMITOMO CHEMICAL CO (JP) 1994-03-02 EP disclosed
EP-0341496-B1 Modified diene polymer rubbers SUMITOMO CHEMICAL CO (JP) 1993-10-20 EP disclosed
US-5219938-A Reacting a living polymer of a conjugated diene with a tin or silicon compound and with a nitro compound, a phosphoryl chloride, aminosilane, an acrylamide or an aminovinylsilane; auto tires; impact strength; cold resistance; storage SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-15 US disclosed
US-5128416-A Automobile tire treads SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-07 US disclosed
US-5015692-A Rubbers for tires having impact strength SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-14 US disclosed
US-4957976-A IMPROVED PROPERTIES FOR AUTOMOBILE TIRES, MODIFIED WITH PHOSPHORYL CHLORIDE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1990-09-18 US disclosed
EP-0341496-A2 Modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-11-15 EP disclosed
EP-0270071-A2 Process for preparing modified diene polymer rubbers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-08 EP disclosed