Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1939000 | 0.84 | TDP1 (0.44) | TDP1MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL273486 | 0.79 | TDP1 (0.52) | TDP1MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL16401979 | 0.79 | TDP1 (0.46) | TDP1MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL4394556 | 0.72 | ASAH1 (0.49) | TDP1HTTSMN1; SMN2LMNA | |
| SCHEMBL4075893 | 0.72 | ASAH1 (0.49) | TDP1HTTSMN1; SMN2LMNA | |
| SCHEMBL8013907 | 0.72 | TDP1 (0.52) | TDP1MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL8413080 | 0.71 | TDP1 (0.48) | TDP1CYP11B1CYP11B2TNFHTT | |
| SCHEMBL6445627 | 0.71 | MEN1 (0.42) | TDP1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6381049 | 0.69 | TDP1 (0.48) | TDP1MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL20683088 | 0.69 | TDP1 (0.48) | TDP1MEN1KMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396394-A1 | FATTY SORBITAN ESTER BASED FRICTION MODIFIERS | Chemtura Corporation (US) | 2011-12-21 | — | — | EP | disclosed |
| WO-2010093519-A1 | FATTY SORBITAN ESTER BASED FRICTION MODIFIERS | CHEMTURA CORPORATION (US) | 2010-08-19 | — | — | WO | disclosed |
| EP-1753849-A2 | LUBRICATING COMPOSITIONS CONTAINING SULPHONATES AND PHENATES | The Lubrizol Corporation (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005112575-A2 | LUBRICATING COMPOSITIONS CONTAINING SULPHONATES AND PHENATES | THE LUBRIZOL CORPORATION (US) | 2005-12-01 | — | — | WO | disclosed |