Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273486 | 0.86 | TDP1 (0.52) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL6381049 | 0.83 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL20683088 | 0.83 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL1879818 | 0.79 | HTT (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL9060998 | 0.78 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2TNF | |
| SCHEMBL8413080 | 0.78 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL14722522 | 0.78 | TDP1 (0.44) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL15525424 | 0.78 | TDP1 (0.44) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL8412995 | 0.77 | MEN1 (0.47) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL8792548 | 0.75 | TDP1 (0.46) | TDP1HTTCYP11B1CYP11B2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127574-A | Carbonylation process | BP CHEMICALS LIMITED (GB) | 2000-10-03 | — | — | US | disclosed |
| EP-0103978-B1 | SINGLE STAGE PRODUCTION OF IMPROVED HIGH MOLECULAR WEIGHT POLYBENZIMIDAZOLE | CELANESE CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4481327-A | TIRES OF HIGH GREEN STRENGTH | BRIDGESTONE TIRE COMPANY, LTD. (JP) | 1984-11-06 | — | — | US | disclosed |
| US-4440933-A | HISTAMINE H2-RECEPTOR ANTAGONISTS | BRISTOL-MYERS COMPANY (US) | 1984-04-03 | — | — | US | disclosed |