Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013907 | 0.86 | TDP1 (0.52) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL16401979 | 0.83 | TDP1 (0.46) | TDP1HTTCYP11B1CYP11B2TNF | |
| SCHEMBL6381049 | 0.83 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL20683088 | 0.83 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL1879818 | 0.79 | HTT (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL3805246 | 0.79 | TDP1 (0.42) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL8413080 | 0.78 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL9060998 | 0.78 | TDP1 (0.48) | TDP1HTTCYP11B1CYP11B2TNF | |
| SCHEMBL15525424 | 0.78 | TDP1 (0.44) | TDP1HTTCYP11B1CYP11B2POLB | |
| SCHEMBL14722522 | 0.78 | TDP1 (0.44) | TDP1HTTCYP11B1CYP11B2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176512-A1 | Asymmetric disulfides and methods of using same | PROLX PHARMACEUTICALS CORPORATION (CA) | 2003-09-18 | — | — | US | claimed |
| WO-2023233895-A1 | POLYIMIDE RESIN PRECURSOR | 東京応化工業株式会社 | 2023-12-07 | — | — | WO | disclosed |
| WO-2023233896-A1 | PHOTOSENSITIVE RESIN COMPOSITION | 東京応化工業株式会社 | 2023-12-07 | — | — | WO | disclosed |
| WO-2023176172-A1 | POLYIMIDE RESIN PRECURSOR | 東京応化工業株式会社 | 2023-09-21 | — | — | WO | disclosed |
| US-8530003-B2 | Polybenzoxazole precursor, photosensitive resin composition using the same, and manufacturing method of semiconductor device | FUJIFILM CORPORATION (JP) | 2013-09-10 | — | — | US | disclosed |
| US-20120115333-A1 | POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE | FUJIFILM CORPORATION (JP) | 2012-05-10 | — | — | US | disclosed |
| US-8133550-B2 | Good breaking elongation characteristics, achievable high sensitivity and high film remaining rate, little in pattern size fluctuation at the heating time after lithographic process, capable of stable pattern formation; manufacturing a semiconductor device | FUJIFILM CORPORATION (JP) | 2012-03-13 | — | — | US | disclosed |
| WO-2009082686-A1 | COMPOSITIONS AND METHODS FOR USING ASYMMETRIC DISULFIDES | PROLX PHARMACEUTICALS CORP. (US) | 2009-07-02 | — | — | WO | disclosed |
| US-20080076849-A1 | POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE | FUJIFILM CORPORATION (JP) | 2008-03-27 | — | — | US | disclosed |
| EP-1786477-A2 | METHOD OF PRESELECTION PATIENTS FOR ANTI-VEGF, ANTI-HIF-1 OR ANTI-THIOREDOXIN THERAPY | Prolx Pharmaceuticals Corp. (US) | 2007-05-23 | — | — | EP | disclosed |
| WO-2005007108-A2 | ASYMMETRIC DISULFIDES AND METHODS OF USING SAME | PROLX PHARMACEUTICALS, INC. (US) | 2005-01-27 | — | — | WO | disclosed |
| US-20040116496-A1 | Asymmetric Disulfides and methods of using same | PROLX PHARMACEUTICALS CORP. | 2004-06-17 | — | — | US | disclosed |
| US-20030176512-A1 | Asymmetric disulfides and methods of using same | PROLX PHARMACEUTICALS CORPORATION (CA) | 2003-09-18 | — | — | US | disclosed |
| US-6552060-B1 | Inhibits abnormal cellular proliferation and restores or prevents inhibition of cellular apoptosis | PROLX PHARMACEUTICALS, INC. | 2003-04-22 | — | — | US | disclosed |
| US-4599428-A | SALT FORMATION, THIOETHERIFICATION | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1986-07-08 | — | — | US | disclosed |
| US-4473697-A | WITH GASEOUS CHLORINE AND A RHODANIDE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1984-09-25 | — | — | US | disclosed |
| EP-0027646-B1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1984-03-07 | — | — | EP | disclosed |
| US-4275073-A | PENTATHIEPINOPYRAZOLES AND PYRAZOLOTRITHIOCARBONATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-23 | — | — | US | disclosed |
| EP-0027646-A1 | Process for the preparation of benzimidazole derivatives | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1981-04-29 | — | — | EP | disclosed |
| US-4259344-A | FUNGICIDES, ANTHELMINTICS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115333-A1 | POLYBENZOXAZOLE PRECURSOR, PHOTOSENSITIVE RESIN COMPOSITION USING THE SAME, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE | CD79B, BRIX1, SMARCB1 | TDP1 1732/4885HTT 2882/4885CYP11B1 3379/4885 |
| US-20030176512-A1 | Asymmetric disulfides and methods of using same | PRDX3, PDIA5, PRDX5 | TDP1 3261/4885HTT 2505/4885CYP11B1 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.