Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.47 |
| ▸ | RORA | P35398 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RORB | Q92753 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157974 | 0.86 | NPSR1 (0.54) | PIK3CGPIK3CAPIK3CDPIK3CBRORA | |
| SCHEMBL6431189 | 0.79 | PIK3CG (0.45) | PIK3CGPIK3CAPIK3CDPIK3CBRORA | |
| SCHEMBL3816575 | 0.77 | NPSR1 (0.67) | NPSR1KDM4ERXFP1 | |
| SCHEMBL3812255 | 0.77 | NPSR1 (0.50) | NPSR1KDM4ERXFP1ALDH1A1LMNA | |
| SCHEMBL6823767 | 0.76 | RORA (0.54) | PIK3CGPIK3CAPIK3CDPIK3CBRORA | |
| SCHEMBL3816632 | 0.76 | NPSR1 (0.49) | NPSR1KDM4ERXFP1ALDH1A1MEN1 | |
| SCHEMBL3811715 | 0.76 | NPSR1 (0.69) | NPSR1KDM4ERXFP1LMNAMEN1 | |
| SCHEMBL17599331 | 0.76 | PIK3CG (0.45) | PIK3CGPIK3CAPIK3CDPIK3CBRORA | |
| SCHEMBL3817684 | 0.75 | NPSR1 (0.47) | NPSR1KDM4ERXFP1ALDH1A1LMNA | |
| SCHEMBL3815606 | 0.75 | ACLY (0.59) | NPSR1KDM4ERXFP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |