Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 7/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.72 |
| ▸ | CA12 | O43570 | 4/20 | 0.72 |
| ▸ | PPARG | P37231 | 4/20 | 0.72 |
| ▸ | CA7 | P43166 | 4/20 | 0.72 |
| ▸ | XDH | P47989 | 4/20 | 0.72 |
| ▸ | CA2 | P00918 | 3/20 | 0.72 |
| ▸ | IPMK | Q8NFU5 | 3/20 | 0.72 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.72 |
| ▸ | CA4 | P22748 | 3/20 | 0.72 |
| ▸ | BCL9 | O00512 | 9/20 | 0.63 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.63 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807701 | 0.93 | CYP1A2 (0.71) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL117682 | 0.86 | CYP1A2 (0.73) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL3718642 | 0.85 | MEN1 (0.72) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL19235 | 0.84 | MEN1 (1.00) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL29377152 | 0.84 | MEN1 (1.00) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL29390102 | 0.84 | MEN1 (1.00) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Isorhamnetin SCHEMBL30385934 | 0.84 | MEN1 (1.00) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| SCHEMBL3718774 | 0.83 | MEN1 (0.71) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Quercetin-3'-O-Phosphate SCHEMBL118113 | 0.83 | CYP1A2 (0.73) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 | |
| Quercetin-3'-O-Phosphate SCHEMBL30299021 | 0.83 | CYP1A2 (0.73) | CYP1A2MEN1KMT2ACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100297020-A1 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | LIMERICK BIOPHARMA, INC. (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297020-A1 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | PC, PCK1, PYGL | CYP1A2 2311/4885MEN1 2302/4885KMT2A 4512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.