Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807257 | 0.90 | KDM4E (0.39) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL2157821 | 0.88 | PTPN1 (0.48) | MAPTMEN1KMT2ARAB9APTPN1 | |
| SCHEMBL3812117 | 0.87 | HSD17B1 (0.39) | MAPTRAB9A | |
| SCHEMBL2879446 | 0.86 | GRM5 (0.36) | MAPTMEN1KMT2A | |
| SCHEMBL3809145 | 0.85 | TRPV1 (0.38) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL3814712 | 0.84 | AKR1C3 (0.37) | KMT2AAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL3814842 | 0.83 | IKBKB (0.38) | MAPTRAB9APTPN1 | |
| SCHEMBL3808983 | 0.83 | MAPT (0.36) | MAPTMEN1KMT2ARAB9APTPN1 | |
| SCHEMBL3816814 | 0.82 | KDM4E (0.39) | MAPTMEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL3816914 | 0.82 | MMP1 (0.36) | KMT2AAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |