Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814674 | 0.88 | GAA (0.40) | ALDH1A1KDM4EMAPTHPGDHTT | |
| SCHEMBL2157712 | 0.86 | — | — | |
| SCHEMBL3811068 | 0.80 | KDM4E (0.39) | KDM4EMAPT | |
| SCHEMBL3816733 | 0.78 | HPGD (0.36) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3816963 | 0.76 | USP2 (0.41) | KDM4EMAPTHTT | |
| SCHEMBL3816881 | 0.75 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3815360 | 0.75 | KDM4E (0.38) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL2158088 | 0.75 | — | — | |
| SCHEMBL3812533 | 0.74 | MAPT (0.38) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3807569 | 0.74 | HSD17B1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |