Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814714 | 0.96 | HSD17B1 (0.41) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL3812444 | 0.91 | ALDH1A1 (0.36) | MAPTNPSR1MEN1ALDH1A1KMT2A | |
| SCHEMBL3811068 | 0.91 | KDM4E (0.39) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL3815494 | 0.89 | ALOX15 (0.35) | KDM4ENPC1MAPTRAB9AIDO1 | |
| SCHEMBL3816598 | 0.89 | MAPT (0.35) | KDM4ENPC1MAPTRAB9AHPGD | |
| SCHEMBL3812533 | 0.89 | MAPT (0.38) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL3809515 | 0.88 | IKBKB (0.39) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL3817251 | 0.87 | MAPT (0.37) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL3807344 | 0.86 | MAPT (0.36) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL3816699 | 0.86 | KDM4E (0.36) | KDM4ENPC1MAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |