Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ACLY | P53396 | 4/20 | 0.56 |
| ▸ | PGR | P06401 | 3/20 | 0.52 |
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816575 | 0.91 | NPSR1 (0.67) | NPSR1ACLYKDM4ERXFP1 | |
| SCHEMBL3814727 | 0.90 | NPSR1 (0.57) | NPSR1ACLYCCR2KDM4ERXFP1 | |
| SCHEMBL3809449 | 0.88 | ACLY (0.55) | NPSR1ACLYPGRCCR2KDM4E | |
| SCHEMBL3814467 | 0.87 | NPSR1 (0.57) | NPSR1ACLYKDM4ERXFP1 | |
| SCHEMBL3816646 | 0.86 | NPSR1 (0.56) | NPSR1ACLYPGRKDM4ERXFP1 | |
| SCHEMBL3815278 | 0.86 | NPSR1 (0.56) | NPSR1ACLYPGRKDM4ERXFP1 | |
| SCHEMBL3813310 | 0.85 | NPSR1 (0.52) | NPSR1ACLYKDM4ERXFP1 | |
| SCHEMBL3811270 | 0.85 | IKBKB (0.53) | NPSR1ACLYKDM4ERXFP1 | |
| SCHEMBL3815210 | 0.84 | ITGA1 (0.49) | NPSR1ACLY | |
| SCHEMBL3812301 | 0.84 | NPSR1 (0.43) | NPSR1KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |