Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 2/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 5/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816592 | 0.90 | TRIM24 (0.46) | NPSR1ACLY | |
| SCHEMBL3811541 | 0.90 | NPSR1 (0.48) | NPSR1ACLY | |
| SCHEMBL3812093 | 0.87 | NPSR1 (0.46) | NPSR1ACLY | |
| SCHEMBL3814727 | 0.85 | NPSR1 (0.57) | NPSR1ACLY | |
| SCHEMBL3809012 | 0.84 | NPSR1 (0.56) | NPSR1ACLY | |
| SCHEMBL3812301 | 0.84 | NPSR1 (0.43) | NPSR1 | |
| SCHEMBL3809155 | 0.84 | NPSR1 (0.49) | NPSR1ACLY | |
| SCHEMBL3816724 | 0.84 | ACLY (0.47) | PTGDR2NPSR1ACLY | |
| SCHEMBL3807904 | 0.84 | HSD17B1 (0.48) | NPSR1 | |
| SCHEMBL3809025 | 0.83 | ACLY (0.58) | NPSR1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |