Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 3/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811541 | 0.89 | NPSR1 (0.48) | NPSR1MAPTKDM4ERXFP1ACLY | |
| SCHEMBL3812255 | 0.87 | NPSR1 (0.50) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3807309 | 0.86 | NPSR1 (0.48) | NPSR1MAPTKDM4ERXFP1ACLY | |
| SCHEMBL3813310 | 0.85 | NPSR1 (0.52) | NPSR1KDM4ERXFP1ACLYIKBKB | |
| SCHEMBL3809449 | 0.85 | ACLY (0.55) | NPSR1KDM4ERXFP1ACLYIKBKB | |
| SCHEMBL3816575 | 0.85 | NPSR1 (0.67) | NPSR1KDM4ERXFP1ACLYIKBKB | |
| SCHEMBL3814727 | 0.85 | NPSR1 (0.57) | NPSR1KDM4ERXFP1ACLYIKBKB | |
| SCHEMBL3815281 | 0.85 | SMN1; SMN2 (0.55) | NPSR1MAPTKDM4ERXFP1 | |
| SCHEMBL3812093 | 0.84 | NPSR1 (0.46) | NPSR1MAPTKDM4ERXFP1ACLY | |
| SCHEMBL3815210 | 0.84 | ITGA1 (0.49) | NPSR1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |