SCHEMBL380975

SCHEMBL380975

CCCNC(=O)/C=C\C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
LMNA P02545 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MAPT P10636 4/20 0.40
HTT P42858 3/20 0.40
PKM P14618 1/20 0.40
NLRP1 Q9C000 1/20 0.40
DDAH1 O94760 1/20 0.39
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
ZDHHC20 Q5W0Z9 3/20 0.38
ZDHHC2 Q9UIJ5 3/20 0.38
MCL1 Q07820 2/20 0.38
EPHX1 P07099 1/20 0.38
PELI1 Q96FA3 2/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
EGFR P00533 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL380976 1.00 ALDH1A1 (0.44) ALDH1A1LMNASMN1; SMN2MAPTHTT
Ammonia Solution, Strong SCHEMBL2389741 0.98 ALDH1A1 (0.42) ALDH1A1LMNASMN1; SMN2MAPTHTT
Ammonia Solution, Strong SCHEMBL2389744 0.98 ALDH1A1 (0.42) ALDH1A1LMNASMN1; SMN2MAPTHTT
SCHEMBL1700849 0.89 ALDH1A1 (0.50) ALDH1A1LMNASMN1; SMN2MAPTHTT
SCHEMBL2536904 0.89 ALDH1A1 (0.50) ALDH1A1LMNASMN1; SMN2MAPTHTT
SCHEMBL3105960 0.88 ZDHHC20 (0.48) ALDH1A1MAPTHTTMMP2ZDHHC20
SCHEMBL380522 0.88 ZDHHC20 (0.48) ALDH1A1MAPTHTTMMP2ZDHHC20
SCHEMBL380523 0.88 ZDHHC20 (0.48) ALDH1A1MAPTHTTMMP2ZDHHC20
SCHEMBL7032175 0.86 ALDH1A1 (0.36) ALDH1A1LMNASMN1; SMN2MAPTHTT
SCHEMBL9653609 0.86 ZDHHC20 (0.56) ALDH1A1ZDHHC20ZDHHC2EPHX1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2223995-B2 CLEANING AGENT FOR REMOVING PAINT LAYERS ON SURFACES, METHOD FOR MANUFACTURING THE AGENT AND CLEANING METHOD INTELLIGENT FLUIDS GMBH (DE) 2024-12-11 EP claimed
EP-2223995-B1 CLEANING AGENT FOR REMOVING PAINT LAYERS ON SURFACES, METHOD FOR MANUFACTURING THE AGENT AND CLEANING METHOD INTELLIGENTS FLUIDS GMBH (DE) 2018-03-07 EP claimed
EP-3055401-A1 PHOTORESIST STRIPPING USING INTELLIGENT LIQUIDS Bubbles and Beyond GmbH (DE) 2016-08-17 EP claimed
CN-101861381-B Formulation for removing coloured coatings and various fouling layers from surfaces, method for preparing such an agent and cleaning method Foam & Beyond Ltd. (DE) 2016-03-30 CN claimed
WO-2015052347-A1 PHOTORESIST STRIPPING USING INTELLIGENT LIQUIDS BUBBLES & BEYOND (DE) 2015-04-16 WO claimed
US-20120085371-A1 METHOD AND COMPOSITION FOR CLEANING OBJECTS BUBBLES AND BEYOND GMBH (DE) 2012-04-12 US claimed
CN-102388123-A Method and composition for cleaning articles BUBBLES AND BEYOND GMBH 2012-03-21 CN claimed
US-20120064011-A1 PREPARATION FOR EXTERNAL APPLICATION BUBBLES AND BEYOND GMBH (DE) 2012-03-15 US claimed
EP-2408429-A2 PREPARATION FOR EXTERNAL APPLICATION Bubbles and Beyond GmbH (DE) 2012-01-25 EP claimed
US-20110229424-A1 FORMULA FOR REMOVING COLOR COATS AND VARIOUS SOIL LAYERS FROM SURFACES, METHOD FOR PRODUCING THE AGENT, AND METHOD FOR CLEANING BUBBLES & BEYOND GMBH 2011-09-22 US claimed
WO-2010105842-A2 PREPARATION FOR EXTERNAL APPLICATION BUBBLES AND BEYOND GMBH (DE) 2010-09-23 WO claimed
EP-2223995-A2 Formulas for removing paint layers and diverse dirt coatings on surfaces, method for manufacturing the agent and cleaning method Bubbles and Beyond GmbH (DE) 2010-09-01 EP claimed
EP-2195408-A2 FORMULA FOR REMOVING COLOR COATS AND VARIOUS SOIL LAYERS FROM SURFACES, METHOD FOR PRODUCING THE AGENT, AND METHOD FOR CLEANING Bubbles & Beyond Gmbh (DE) 2010-06-16 EP claimed
EP-1660507-B9 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON INC (US) 2010-03-24 EP claimed
US-20090291918-A1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2009-11-26 US claimed
EP-1660507-B1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON INC (US) 2009-08-05 EP claimed
WO-2009037349-A2 FORMULA FOR REMOVING COLOR COATS AND VARIOUS SOIL LAYERS FROM SURFACES, METHOD FOR PRODUCING THE AGENT, AND METHOD FOR CLEANING BUBBLES & BEYOND GMBH (DE) 2009-03-26 WO claimed
EP-1660507-A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2006-05-31 EP claimed
US-20050107307-A1 Proteasome inhibitors and methods of using the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-05-19 US claimed
WO-2005021558-A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2005-03-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090291918-A1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME PSMB11, PSMB5, PSMB6 ALDH1A1 3935/4885LMNA 770/4885SMN1; SMN2 1107/4885
US-20050107307-A1 Proteasome inhibitors and methods of using the same PSMB11, PSMB5, PSMB6 ALDH1A1 3935/4885LMNA 770/4885SMN1; SMN2 1107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.