Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380975 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL380976 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| Ammonia Solution, Strong SCHEMBL2389741 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| Ammonia Solution, Strong SCHEMBL2389744 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL1700849 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL2536904 | 0.76 | ALDH1A1 (0.50) | ALDH1A1LMNASMN1; SMN2MAPTHTT | |
| SCHEMBL3419359 | 0.76 | MMP1 (0.30) | MMP1MMP2MMP3MMP9 | |
| SCHEMBL3105960 | 0.75 | ZDHHC20 (0.48) | ALDH1A1MAPTHTTZDHHC20ZDHHC2 | |
| SCHEMBL380522 | 0.75 | ZDHHC20 (0.48) | ALDH1A1MAPTHTTZDHHC20ZDHHC2 | |
| SCHEMBL380523 | 0.75 | ZDHHC20 (0.48) | ALDH1A1MAPTHTTZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030004172-A1 | Fused pyrimidinone matrix metalloproteinase inhibitors | HARTER WILLIAM GLEN (US) | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004172-A1 | Fused pyrimidinone matrix metalloproteinase inhibitors | MMP13, MMP3, MMP25 | ALDH1A1 812/4885LMNA 1210/4885SMN1; SMN2 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.