Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19244867 | 0.91 | OPRM1 (0.42) | CXCL8OPRM1ADRB2ADRB1CYP2D6 | |
| SCHEMBL381522 | 0.90 | MEN1 (0.35) | KMT2AMEN1ITGAVCXCL8OPRM1 | |
| SCHEMBL19244878 | 0.82 | OPRM1 (0.39) | KMT2AMEN1CXCL8OPRM1ADRB2 | |
| SCHEMBL19244855 | 0.81 | MEN1 (0.41) | KMT2AMEN1CXCL8OPRM1CYP2D6 | |
| SCHEMBL417713 | 0.81 | OPRM1 (0.38) | KMT2AMEN1ITGAVOPRM1 | |
| SCHEMBL381393 | 0.80 | NISCH (0.43) | KMT2AMEN1CXCL8CYP2D6NFKB1 | |
| SCHEMBL19244883 | 0.80 | OPRM1 (0.41) | KMT2AMEN1CXCL8OPRM1ADRB2 | |
| SCHEMBL381228 | 0.79 | MEN1 (0.39) | KMT2AMEN1CXCL8OPRM1CYP2D6 | |
| SCHEMBL382042 | 0.79 | CNR2 (0.40) | KMT2AMEN1HSD11B1 | |
| SCHEMBL19244879 | 0.76 | MEN1 (0.37) | KMT2AMEN1CXCL8CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408751-B1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| EP-2408751-A1 | Substituted 2-acetamido-5-aryl-1,2,4-triazolones and use thereof | Bayer Pharma Aktiengesellschaft (DE) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105770-A1 | SUBSTITUTED 2-ACETAMIDO-5-ARYL-1,2,4-TRIAZOLONES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-09-23 | — | — | WO | disclosed |