Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PYGB | P11216 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934741 | 0.89 | CA1 (0.50) | CA1CA2CA9AKR1B1PYGB | |
| SCHEMBL7253811 | 0.89 | CA1 (0.50) | CA1CA2CA9AKR1B1PYGB | |
| SCHEMBL9616492 | 0.89 | CA1 (0.50) | CA1CA2CA9AKR1B1PYGB | |
| SCHEMBL18642492 | 0.89 | CA1 (0.50) | CA1CA2CA9AKR1B1PYGB | |
| SCHEMBL3810831 | 0.89 | CA1 (0.50) | CA1CA2CA9AKR1B1PYGB | |
| SCHEMBL4886455 | 0.85 | CA1 (0.37) | CA1CA2CA9AKR1B1PYGB | |
| SCHEMBL4251158 | 0.82 | FBP1 (0.47) | — | |
| SCHEMBL4885009 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL3814606 | 0.78 | PYGB (0.40) | CA1CA2CA9AKR1B1PYGB | |
| SCHEMBL3816161 | 0.77 | CA1 (0.37) | CA1CA2CA9AKR1B1PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863497-A4 | METHODS, COMPOSITIONS, AND FORMULATIONS FOR PREVENTING OR REDUCING ADVERSE EFFECTS IN A PATIENT | PERICOR THERAPEUTICS INC (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1863497-A2 | METHODS, COMPOSITIONS, AND FORMULATIONS FOR PREVENTING OR REDUCING ADVERSE EFFECTS IN A PATIENT | Pericor Therapeutics, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006105167-A2 | METHODS, COMPOSITIONS, AND FORMULATIONS FOR PREVENTING OR REDUCING ADVERSE EFFECTS IN A PATIENT | PERICOR THERAPEUTICS, INC. (US) | 2006-10-05 | — | — | WO | disclosed |