SCHEMBL381018

SCHEMBL381018

CCC(C)(O)CCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP1A2 P05177 1/20 0.50
THRB P10828 1/20 0.50
HMGCR P04035 1/20 0.46
CHRM1 P11229 1/20 0.46
TBXA2R P21731 1/20 0.46
ADRA1A P35348 1/20 0.46
FFAR3 O14843 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
NAALAD2 Q9Y3Q0 1/20 0.43
ESR1 P03372 2/20 0.39
CYP3A4 P08684 1/20 0.39
ESR2 Q92731 1/20 0.39
AKR1B1 P15121 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28948540 1.00 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL380377 0.86 AKR1B1 (0.46) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL381124 0.84 AKR1B1 (0.50) ALDH1A1MEN1KMT2AHMGCRCHRM1
SCHEMBL381115 0.83 FFAR3 (0.48) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL11061139 0.82 GPR84 (0.52) ALDH1A1MEN1KMT2AESR1AKR1B1
SCHEMBL10414762 0.82 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL9580919 0.80 HMGCR (0.67) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL380059 0.79 AKR1B1 (0.50) ALDH1A1MEN1KMT2AFFAR3HDAC3
SCHEMBL29024479 0.78 HMGCR (0.44) ALDH1A1MEN1KMT2ACYP1A2THRB
SCHEMBL10486544 0.78 HMGCR (0.44) ALDH1A1MEN1KMT2ACYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3793973-B1 PROCESS FOR PRODUCING AN INTRAMOLECULAR DIESTER OF A HYDROXYCARBOXYLIC ACID AND PROCESS FOR PRODUCING A POLYHYDROXYCARBOXYLIC ACID. FRAUNHOFER GES FORSCHUNG (DE) 2022-12-28 EP claimed
EP-3793973-A1 PROCESS FOR PRODUCING AN INTRAMOLECULAR DIESTER OF A HYDROXYCARBOXYLIC ACID AND PROCESS FOR PRODUCING A POLYHYDROXYCARBOXYLIC ACID. FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. (DE) 2021-03-24 EP claimed
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF RAYZEBIO, INC. 2023-05-25 US disclosed
EP-3793973-B1 PROCESS FOR PRODUCING AN INTRAMOLECULAR DIESTER OF A HYDROXYCARBOXYLIC ACID AND PROCESS FOR PRODUCING A POLYHYDROXYCARBOXYLIC ACID. FRAUNHOFER GES FORSCHUNG (DE) 2022-12-28 EP disclosed
US-20210139390-A1 PRODUCTION METHOD OF ORGANIC COMPOUND UNITIKA LTD. (JP) 2021-05-13 US disclosed
EP-3819283-A1 METHOD FOR PRODUCING ORGANIC COMPOUND Unitika Ltd. (JP) 2021-05-12 EP disclosed
EP-3793973-A1 PROCESS FOR PRODUCING AN INTRAMOLECULAR DIESTER OF A HYDROXYCARBOXYLIC ACID AND PROCESS FOR PRODUCING A POLYHYDROXYCARBOXYLIC ACID. FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. (DE) 2021-03-24 EP disclosed
CN-112384489-A Method for producing organic compound 尤尼吉可株式会社 2021-02-19 CN disclosed
WO-2020009016-A1 METHOD FOR PRODUCING ORGANIC COMPOUND ユニチカ株式会社 2020-01-09 WO disclosed
CN-105121504-B The process for purification of aliphatic polyester and the aliphatic polyester refined with this method 株式会社武藏野化学研究所 2018-05-01 CN disclosed
EP-2987815-A1 METHOD FOR PURIFYING ALIPHATIC POLYESTER AND ALIPHATIC POLYESTER PURIFIED WITH SAID METHOD Musashino Chemical Laboratory, Ltd. (JP) 2016-02-24 EP disclosed
US-5616783-A DISSOLVING IN WATER IMMISCIBLE PHENOL-TYPE COMPOUND, CONTACTING WITH WATER CONTAINING ACIDIC MATERIAL, SEPARATING AND ISOLATING MITSUI TOATSU CHEMICALS, INC. (JP) 1997-04-01 US disclosed
EP-0710684-A2 Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-08 EP disclosed
US-5512653-A Lactic acid containing hydroxycarboxylic acid for the preparation of polhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1996-04-30 US disclosed
EP-0707024-A2 Purification process of polyhydroxycarboxylic acids MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-04-17 EP disclosed
US-5444143-A Preparation process of polyhydroxycarboxylic acid MITSUI TOATSU CHEMICALS, INC. (JP) 1995-08-22 US disclosed
US-5440008-A Condensation polymerization of hydroxycarboxylic acids in vertical reactor with ribbon stirrer, having flow pattern along walls in opposite direction to flow along axis of stirrer MITSUI TOATSU CHEMICALS, INC. (JP) 1995-08-08 US disclosed
US-5386004-A Contacting with acid substance in presence of organic solvent MITSUI TOATSU CHEMICALS, INC. (JP) 1995-01-31 US disclosed
EP-0603889-A2 Process for the preparation of lactic acid polyesters MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-06-29 EP disclosed
EP-0591978-A2 Polyhydroxycarboxylic acid and purification process thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1994-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158179-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOSITIONS AND USES THEREOF PAICS, LNPEP, DNPEP ALDH1A1 3285/4885MEN1 58/4885KMT2A 1875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.