SCHEMBL3810754

SCHEMBL3810754

C=CCC(CCCC)O[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.30
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15266065 0.92 TSHR (0.40) TSHRALDH1A1DNM1
SCHEMBL15309367 0.87
SCHEMBL798042 0.83 TSHR (0.39) TSHRALDH1A1SMN1; SMN2DNM1
SCHEMBL2525472 0.83 TSHR (0.39) TSHRALDH1A1SMN1; SMN2DNM1
SCHEMBL16177286 0.81 TSHR (0.37) TSHRALDH1A1SMN1; SMN2DNM1
SCHEMBL3481885 0.79 DNM1 (0.39) TSHRALDH1A1SMN1; SMN2DNM1
SCHEMBL6838265 0.79 TSHR (0.36) TSHRALDH1A1SMN1; SMN2DNM1
SCHEMBL15090866 0.79 ALDH1A1 (0.33) TSHRALDH1A1SMN1; SMN2
SCHEMBL1158829 0.79 TSHR (0.36) TSHRALDH1A1SMN1; SMN2DNM1
SCHEMBL15210243 0.79 TSHR (0.36) TSHRALDH1A1SMN1; SMN2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790350-B2 Method and materials for patterning a neutral surface INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-09-07 US claimed
US-20090035668-A1 Method and materials for patterning a neutral surface GLOBALFOUNDRIES U.S. INC. 2009-02-05 US claimed
US-9790223-B2 Process for preparation of sodium (2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate WOCKHARDT LIMITED (IN) 2017-10-17 US disclosed
EP-3116875-A1 A PROCESS FOR PREPARATION OF SODIUM (2S, 5R)-6-(BENZYLOXY)-7-OXO-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXYLATE Wockhardt Limited (IN) 2017-01-18 EP disclosed
US-20170008892-A1 PROCESS FOR PREPARATION OF SODIUM (2S, 5R)-6-(BENZYLOXY)-7-OXO-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXYLATE WOCKHARDT LIMITED (IN) 2017-01-12 US disclosed
EP-3057944-A1 A NOVEL PROCESS FOR THE PREPARATION OF CHIRAL CYCLOPENTANONE INTERMEDIATES Pharmathen S.A. (GR) 2016-08-24 EP disclosed
WO-2015136473-A1 A PROCESS FOR PREPARATION OF SODIUM (2S, 5R)-6-(BENZYLOXY)-7-OXO-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXYLATE WOCKHARDT LIMITED (IN) 2015-09-17 WO disclosed
WO-2015051903-A1 A NOVEL PROCESS FOR THE PREPARATION OF CHIRAL CYCLOPENTANONE INTERMEDIATES PHARMATHEN S.A. (GR) 2015-04-16 WO disclosed
US-7790350-B2 Method and materials for patterning a neutral surface INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-09-07 US disclosed
US-20090035668-A1 Method and materials for patterning a neutral surface GLOBALFOUNDRIES U.S. INC. 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008892-A1 PROCESS FOR PREPARATION OF SODIUM (2S, 5R)-6-(BENZYLOXY)-7-OXO-1,6-DIAZABICYCLO[3.2.1]OCTANE-2-CARBOXYLATE SCN1B, SCN7A, ANO2 TSHR 2201/4885ALDH1A1 255/4885SMN1; SMN2 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.