Sugi Predict

Sugi Predict / Compounds / SCHEMBL381082

SCHEMBL381082

SCHEMBL381082

CC(C(=O)O)N(C)C(=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABCB1 P08183 2/20 0.53
▸ ALDH1A1 P00352 5/20 0.51
▸ LTA4H P09960 1/20 0.50
▸ MAPT P10636 1/20 0.48
▸ HPGD P15428 1/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ SLC6A2 P23975 1/20 0.46
▸ SLC6A3 Q01959 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ CTSL P07711 2/20 0.45
▸ CTSB P07858 2/20 0.45
▸ CTSS P25774 2/20 0.45
▸ CTSK P43235 2/20 0.45
▸ SIGMAR1 Q99720 1/20 0.44
▸ SLC15A1 P46059 1/20 0.44
▸ CHRNB2 P17787 1/20 0.43
▸ CHRNB4 P30926 1/20 0.43
▸ CHRNA3 P32297 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL381080 1.00 ABCB1 (0.53) ABCB1ALDH1A1LTA4HMAPTHPGD
SCHEMBL7404261 1.00 ABCB1 (0.53) ABCB1ALDH1A1LTA4HMAPTHPGD
SCHEMBL23893394 0.94 LTA4H (0.52) ABCB1ALDH1A1LTA4HMAPTHPGD
SCHEMBL21492669 0.89 ALDH1A1 (0.47) ABCB1ALDH1A1LTA4HMAPTHPGD
SCHEMBL21492202 0.89 ALDH1A1 (0.47) ABCB1ALDH1A1LTA4HMAPTHPGD
SCHEMBL10788987 0.89 ABCB1 (0.59) ABCB1ALDH1A1MAPTHPGDL3MBTL1
SCHEMBL13373979 0.88 L3MBTL1 (0.51) ABCB1ALDH1A1MAPTHPGDL3MBTL1
SCHEMBL8276259 0.87 ABCB1 (0.56) ABCB1ALDH1A1MAPTHPGDL3MBTL1
SCHEMBL21952369 0.86 ABCB1 (0.44) ABCB1ALDH1A1LTA4HMAPTHPGD
SCHEMBL20026385 0.86 ABCB1 (0.50) ABCB1ALDH1A1MAPTHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 — — EP disclosed
US-12545659-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-02-10 — — US disclosed
US-20260001885-A1 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS MERCK SHARP & DOHME (NL) 2026-01-01 — — US disclosed
WO-2025235719-A1 DIMERIC SMAC MIMETICS USEFUL IN HIV THERAPY VIIV HEALTHCARE COMPANY (US) 2025-11-13 — — WO disclosed
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-10-23 — — US disclosed
EP-4613773-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-10 — — EP disclosed
EP-3731869-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-07-23 — — EP disclosed
US-12258341-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2025-03-25 — — US disclosed
US-20250000985-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-01-02 — — US disclosed
US-12168057-B2 IRAK degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2024-12-17 — — US disclosed
US-8058272-B2 Organic compounds NOVARTIS AG (CH) 2011-11-15 — — US disclosed
US-20100048571-A1 Organic Compounds NOVARTIS AG 2010-02-25 — — US disclosed
EP-2086938-A1 ORGANIC COMPOUNDS Novartis AG (CH) 2009-08-12 — — EP disclosed
WO-2008073306-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2008-06-19 — — WO disclosed
US-7342016-B2 Farnesyl protein transferase inhibitors as antitumor agents SCHERING CORPORATION (US) 2008-03-11 — — US disclosed
EP-1453852-B1 SELECTIVE UROKINASE INHIBITORS WILEX AG (DE) 2007-01-17 — — EP disclosed
US-5093524-A 2-(alkylamino)acetamide derivatives FISONS CORPORATION (US) 1992-03-03 — — US disclosed
US-4305949-A ANTIINFLAMMATORY AGENTS AND IMMUNOREGULATORY AGENTS PFIZER INC. (US) 1981-12-15 — — US disclosed
EP-0005070-B1 N-(2-THIAZOLYL)AMIDES AND THEIR USE AS ANTI-INFLAMMATORY AND IMMUNOREGULATORY AGENTS PFIZER INC. (US) 1981-12-09 — — EP disclosed
US-4217355-A N-(I-THIAZOLYL)-A-(SUBSTITUTED AMINO)AMIDES, ANTIINFLAMMATORY, IMMUNOREGULATIVE PFIZER INC. (US) 1980-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545659-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK4 ABCB1 3848/4885ALDH1A1 4348/4885LTA4H 3331/4885
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 ABCB1 2612/4885ALDH1A1 2776/4885LTA4H 818/4885
US-12258341-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK1 ABCB1 2612/4885ALDH1A1 2776/4885LTA4H 818/4885
US-20250000985-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 ABCB1 2612/4885ALDH1A1 2776/4885LTA4H 818/4885
US-12168057-B2 IRAK degraders and uses thereof IRAK2, IRAK3, IRAK1 ABCB1 2612/4885ALDH1A1 2776/4885LTA4H 818/4885
US-20260001885-A1 4-IMIDAZOPYRIDAZIN-1-YL-BENZAMIDES AS BTK INHIBITORS BTK, ABL1, FLT3 ABCB1 581/4885ALDH1A1 4166/4885LTA4H 3399/4885
US-20100048571-A1 Organic Compounds XIAP, BAX, MCL1 ABCB1 111/4885ALDH1A1 2759/4885LTA4H 4043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.