Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.60 |
| ▸ | KDM5A | P29375 | 4/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.50 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 1/20 | 0.41 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5501220 | 0.93 | ITGB3 (0.59) | ITGB3ITGA2BKDM5APHF8KDM2A | |
| SCHEMBL17440475 | 0.93 | ITGB3 (0.67) | ITGB3ITGA2BKDM5APHF8KDM2A | |
| Hydrochloric Acid SCHEMBL29119874 | 0.91 | ITGB3 (0.65) | ITGB3ITGA2BKDM5APHF8KDM2A | |
| SCHEMBL5751261 | 0.91 | ITGB3 (0.69) | ITGB3ITGA2BKDM5APHF8KDM2A | |
| SCHEMBL5495308 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BF2RSLC6A1GABRA5 | |
| SCHEMBL381083 | 0.86 | ITGB3 (0.66) | ITGB3ITGA2BKDM5APHF8KDM2A | |
| SCHEMBL26547239 | 0.85 | NAAA (0.54) | ITGB3ITGA2BKDM5APHF8KDM2A | |
| Hydrochloric Acid SCHEMBL1532653 | 0.84 | ITGB3 (0.64) | ITGB3ITGA2BKDM5APHF8KDM2A | |
| SCHEMBL3317369 | 0.84 | KDM5A (0.67) | ITGB3ITGA2BKDM5APHF8KDM2A | |
| SCHEMBL1499918 | 0.84 | KDM5A (0.67) | ITGB3ITGA2BKDM5APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317407-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | Seattle Children's Hospital (dba Seattle Children's Research Institute) | 2021-10-14 | — | — | US | disclosed |