Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270878 | 0.80 | PTPN1 (0.46) | PTPN1PTPRFALDH1A1MAPTKDM4E | |
| SCHEMBL2158083 | 0.80 | PTPN1 (0.58) | PTPN1PTPRFMAPTKDM4EIKBKB | |
| SCHEMBL3817330 | 0.77 | PTPN1 (0.50) | PTPN1PTPRFMAPTIKBKBMEN1 | |
| SCHEMBL16425579 | 0.76 | RAB9A (0.59) | L3MBTL1MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL2250633 | 0.74 | PTPN1 (0.52) | PTPN1PTPRFALDH1A1MAPTKDM4E | |
| SCHEMBL2252377 | 0.74 | PTPN1 (0.55) | PTPN1PTPRFALDH1A1MAPTKDM4E | |
| SCHEMBL2250470 | 0.74 | PTPN1 (0.52) | PTPN1PTPRFMAPTIKBKBMEN1 | |
| SCHEMBL2254388 | 0.74 | PTPN1 (0.52) | PTPN1PTPRFMAPTIKBKBMEN1 | |
| SCHEMBL12357351 | 0.74 | PTPN1 (0.61) | PTPN1PTPRFMAPTIKBKBMEN1 | |
| SCHEMBL16413260 | 0.74 | NPC1 (0.55) | PTPN1PTPRFL3MBTL1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |
| US-6881741-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VIROCHEM PHARMA INC. (CA) | 2005-04-19 | — | — | US | claimed |