Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 11/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811557 | 0.96 | CPB1 (0.49) | CPB1LMNASMN1; SMN2NR1H4MEN1 | |
| SCHEMBL3811171 | 0.94 | CNR2 (0.45) | CPB1LMNASMN1; SMN2NR1H4MEN1 | |
| SCHEMBL3811160 | 0.94 | CNR1 (0.45) | CPB1LMNASMN1; SMN2NR1H4MAPT | |
| SCHEMBL3807293 | 0.93 | KDM4E (0.45) | CPB1LMNASMN1; SMN2NR1H4MEN1 | |
| SCHEMBL3815608 | 0.91 | NR1H4 (0.48) | CPB1LMNASMN1; SMN2NR1H4 | |
| SCHEMBL3812112 | 0.91 | PTGES (0.45) | CPB1NR1H4KMT2AMAPT | |
| SCHEMBL3807190 | 0.90 | NR1H4 (0.42) | CPB1LMNASMN1; SMN2NR1H4 | |
| SCHEMBL3811469 | 0.89 | CPB1 (0.43) | CPB1NR1H4MEN1KMT2AKDM4E | |
| SCHEMBL3807405 | 0.89 | CPB1 (0.43) | CPB1SMN1; SMN2NR1H4MEN1KMT2A | |
| SCHEMBL3811131 | 0.89 | NR1H4 (0.49) | CPB1NR1H4HTTMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |