Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815088 | 0.96 | CPB1 (0.43) | KDM4EMEN1HTTKMT2ANR1H4 | |
| SCHEMBL3811147 | 0.93 | CPB1 (0.47) | KDM4EMEN1HTTKMT2ANR1H4 | |
| SCHEMBL3811171 | 0.91 | CNR2 (0.45) | KDM4EMEN1HTTKMT2ANR1H4 | |
| SCHEMBL3811557 | 0.89 | CPB1 (0.49) | KDM4EMEN1HTTKMT2ANR1H4 | |
| SCHEMBL3812112 | 0.89 | PTGES (0.45) | KMT2ANR1H4CPB1MAPT | |
| SCHEMBL3811160 | 0.87 | CNR1 (0.45) | NR1H4CPB1LMNASMN1; SMN2MAPT | |
| SCHEMBL3807405 | 0.87 | CPB1 (0.43) | KDM4EMEN1HTTKMT2ANR1H4 | |
| SCHEMBL3815202 | 0.87 | HSD17B1 (0.39) | MEN1KMT2AMAPT | |
| SCHEMBL3807291 | 0.86 | CPB1 (0.43) | KDM4EMEN1HTTKMT2ANR1H4 | |
| SCHEMBL3811131 | 0.86 | NR1H4 (0.49) | HTTNR1H4CPB1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |