Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2251159 | 0.89 | LNPEP (0.39) | MAPTTHRBNPC1RAB9APTGDR2 | |
| SCHEMBL2157555 | 0.81 | HTT (0.37) | MAPTTHRBHTTTSHR | |
| SCHEMBL3811523 | 0.81 | CYP2E1 (0.32) | — | |
| SCHEMBL3815964 | 0.81 | SLC6A12 (0.34) | NPC1RAB9APTGDR2ALDH1A1SLC6A12 | |
| SCHEMBL2107658 | 0.77 | HTT (0.38) | ALDH1A1HTTTSHR | |
| SCHEMBL2107025 | 0.76 | SERPINE1 (0.38) | ALDH1A1HTTLMNATSHR | |
| SCHEMBL2158689 | 0.74 | CYP1A2 (0.40) | MAPTTSHR | |
| SCHEMBL3811676 | 0.73 | SLC6A12 (0.35) | NPC1RAB9ASLC6A12 | |
| SCHEMBL2157968 | 0.73 | SMN1; SMN2 (0.40) | NPC1RAB9AHTTFDFT1 | |
| SCHEMBL3808991 | 0.72 | SLC6A12 (0.33) | NPC1RAB9AALDH1A1SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |