Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158250 | 0.89 | ENPP2 (0.37) | NPC1RAB9A | |
| SCHEMBL3815964 | 0.83 | SLC6A12 (0.34) | SLC6A12NPC1RAB9AALDH1A1 | |
| SCHEMBL6429208 | 0.83 | PDK2 (0.38) | — | |
| SCHEMBL3811676 | 0.83 | SLC6A12 (0.35) | SLC6A12NPC1RAB9A | |
| SCHEMBL3814662 | 0.80 | MEN1 (0.37) | — | |
| SCHEMBL14865860 | 0.79 | CYP1A2 (0.35) | — | |
| SCHEMBL3814854 | 0.79 | MEN1 (0.39) | — | |
| SCHEMBL3811287 | 0.78 | MEN1 (0.34) | ALDH1A1 | |
| SCHEMBL2157491 | 0.76 | SLC6A2 (0.42) | — | |
| SCHEMBL3808918 | 0.76 | MEN1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |