Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812315 | 0.91 | MAPT (0.40) | MAPTTP53 | |
| SCHEMBL3811571 | 0.91 | ACLY (0.54) | ACLYMAPTTP53 | |
| SCHEMBL3816560 | 0.89 | HSD17B1 (0.44) | LMNAOXTR | |
| SCHEMBL3811162 | 0.88 | GPBAR1 (0.44) | ACLY | |
| SCHEMBL3807545 | 0.88 | HSD17B1 (0.46) | ACLY | |
| SCHEMBL3816953 | 0.86 | NR1H4 (0.41) | MAPTL3MBTL1OXTR | |
| SCHEMBL3809443 | 0.85 | HTR2C (0.41) | MAPTTP53LMNA | |
| SCHEMBL3807286 | 0.85 | CYP1A2 (0.41) | ACLY | |
| SCHEMBL3811062 | 0.84 | HSD17B1 (0.43) | LMNAGRM1 | |
| SCHEMBL3809473 | 0.84 | HSD17B1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |