Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811484 | 0.91 | ACLY (0.43) | ACLYMAPTTP53 | |
| SCHEMBL3811162 | 0.86 | GPBAR1 (0.44) | ACLYGPBAR1 | |
| SCHEMBL3812631 | 0.85 | ACLY (0.41) | ACLYMAPT | |
| SCHEMBL3816560 | 0.84 | HSD17B1 (0.44) | HSD17B1HSD17B2 | |
| SCHEMBL3809712 | 0.83 | POLB (0.50) | ACLYMAPTTP53HSD17B1HSD17B2 | |
| SCHEMBL3807545 | 0.83 | HSD17B1 (0.46) | ACLYHSD17B1HSD17B2 | |
| SCHEMBL2158132 | 0.83 | ACLY (0.59) | ACLYGPBAR1MAPT | |
| SCHEMBL3807286 | 0.83 | CYP1A2 (0.41) | ACLYGPBAR1 | |
| SCHEMBL3811152 | 0.81 | HSD17B1 (0.38) | MAPTHSD17B1HSD17B2 | |
| SCHEMBL3816953 | 0.81 | NR1H4 (0.41) | MAPTHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |