Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814610 | 0.97 | ALOX15 (0.38) | LTB4R2GSTO1ALOX15ALDH1A1MAPT | |
| SCHEMBL3814789 | 0.87 | MAPT (0.38) | GSTO1ALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL3811544 | 0.85 | LTB4R2 (0.43) | LTB4R2ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL3812671 | 0.85 | ALOX15 (0.41) | LTB4R2ALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL3809836 | 0.82 | ALOX15 (0.40) | LTB4R2ALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL3814608 | 0.82 | LTB4R2 (0.40) | LTB4R2ALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL3807301 | 0.82 | GSTO1 (0.35) | GSTO1ALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL3815173 | 0.82 | MAPT (0.36) | GSTO1ALOX15ALDH1A1MAPTHPGD | |
| SCHEMBL3809475 | 0.81 | TP53 (0.43) | ALOX15ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL3816570 | 0.81 | TP53 (0.36) | GSTO1ALOX15ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |