Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814874 | 0.87 | LTB4R2 (0.40) | ATMALOX15HSD17B10ALDH1A1MAPT | |
| SCHEMBL3809645 | 0.86 | HTT (0.38) | GSTO1KDM4EHTTATMALOX15 | |
| SCHEMBL3807299 | 0.85 | PTPRF (0.36) | KDM4EHTTATMALOX15MEN1 | |
| SCHEMBL3812096 | 0.83 | NR1H4 (0.43) | HTTATMMEN1KMT2AALDH1A1 | |
| SCHEMBL3812570 | 0.83 | LTB4R2 (0.39) | HTTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL3811546 | 0.82 | LTB4R2 (0.39) | GSTO1KDM4EALOX15HSD17B10MEN1 | |
| SCHEMBL3811085 | 0.81 | NR1H4 (0.41) | ATMMEN1KMT2ARAB9A | |
| SCHEMBL3814610 | 0.81 | ALOX15 (0.38) | GSTO1KDM4EALOX15HSD17B10MEN1 | |
| SCHEMBL3814789 | 0.81 | MAPT (0.38) | GSTO1KDM4EHTTALOX15HSD17B10 | |
| SCHEMBL3809448 | 0.81 | LTB4R2 (0.38) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |