Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 8/20 | 0.48 |
| ▸ | GAB1 | Q13480 | 4/20 | 0.48 |
| ▸ | IRS1 | P35568 | 3/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157518 | 0.86 | NPSR1 (0.60) | TRPV1MCL1NPSR1METAP2KDM4E | |
| SCHEMBL3816575 | 0.85 | NPSR1 (0.67) | MCL1NPSR1METAP2KDM4ERXFP1 | |
| SCHEMBL3813398 | 0.83 | METAP2 (0.43) | MCL1NPSR1METAP2 | |
| SCHEMBL3811715 | 0.83 | NPSR1 (0.69) | MCL1NPSR1METAP2KDM4ERXFP1 | |
| SCHEMBL3807620 | 0.82 | NPSR1 (0.57) | MCL1NPSR1METAP2KDM4ERXFP1 | |
| SCHEMBL3814727 | 0.82 | NPSR1 (0.57) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3815310 | 0.81 | NPSR1 (0.62) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3811274 | 0.80 | HSD17B2 (0.56) | MCL1NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3810994 | 0.80 | NPSR1 (0.55) | MCL1NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3816150 | 0.79 | ACLY (0.55) | NPSR1KDM4ERXFP1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |