SCHEMBL381244

SCHEMBL381244

N#CSc1ccc([N+](=O)[O-])c(C(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DTYMK P23919 1/20 0.69
TSHR P16473 3/20 0.43
CASP6 P55212 1/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
POLB P06746 2/20 0.40
LMNA P02545 2/20 0.40
TDP1 Q9NUW8 2/20 0.38
TTR P02766 1/20 0.38
PPOX P50336 1/20 0.38
BCL2L1 Q07817 1/20 0.38
MAPT P10636 3/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
GFER P55789 1/20 0.36
GSTP1 P09211 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxyamine SCHEMBL31741821 0.97 DTYMK (0.66) DTYMKTSHRCASP6MEN1KMT2A
SCHEMBL28277467 0.83 SIRT6 (0.49) DTYMKMEN1KMT2ALMNATDP1
SCHEMBL143541 0.82 DTYMK (1.00) DTYMKTSHRCASP6MEN1KMT2A
SCHEMBL26775 0.82 DTYMK (1.00) DTYMKTSHRCASP6MEN1KMT2A
SCHEMBL504562 0.82 DTYMK (0.81) DTYMKTSHRCASP6MEN1KMT2A
SCHEMBL29353295 0.82 DTYMK (1.00) DTYMKTSHRCASP6MEN1KMT2A
SCHEMBL29388000 0.81 DTYMK (0.97) DTYMKTSHRCASP6MEN1KMT2A
SCHEMBL8577281 0.81 DTYMK (0.97) DTYMKTSHRCASP6MEN1KMT2A
SCHEMBL2470206 0.81 DTYMK (0.78) DTYMKTSHRCASP6MEN1KMT2A
Propionitrile SCHEMBL5577929 0.80 DTYMK (0.76) DTYMKTSHRCASP6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1670 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079838-A Preparation method of 2-nitro-5-thiocyanobenzoic acid 2026-05-26 CN claimed
EP-4737471-A1 METHODS FOR THE C-TERMINAL MODIFICATION OF (POLY)PEPTIDES NUMAFERM GmbH (DE) 2026-05-06 EP claimed
US-12577602-B2 Compositions and methods for peptide production BIOCATALYST LLC (US) 2026-03-17 US claimed
US-12570688-B2 Activated cysteine-directed polypeptide ligation technique THE TEXAS A&M UNIVERSITY SYSTEM (US) 2026-03-10 US claimed
EP-3765857-B1 SEQUENTIAL DIGESTION OF POLYPEPTIDES FOR MASS SPECTROMETRIC ANALYSIS AMGEN INC (US) 2025-12-10 EP claimed
EP-4150348-B1 SAMPLE PREPARATION FOR MASS SPECTROMETRY PREOMICS GMBH (DE) 2025-11-12 EP claimed
US-20250340858-A1 COMPOSITIONS AND METHODS FOR PREVENTING DEBRIS LAYER FORMATION DURING PHASE SEPARATION IN AN ATPS-SAMPLE LYSATE MIXTURE PHASE SCIENT INTERNATIONAL LTD (CN) 2025-11-06 US claimed
US-12410461-B2 Method of preparing clinical samples for nucleic acid amplification DAY ZERO DIAGNOSTICS, INC. (US) 2025-09-09 US claimed
US-12405275-B2 Methods for the preparation of trypsin-resistant polypeptides for mass spectrometric analysis AMGEN INC. (US) 2025-09-02 US claimed
US-12319909-B2 Compositions and methods for ribonucleic acid extraction Phase Scientific International, Ltd. (CN) 2025-06-03 US claimed
WO-2002086081-A2 METHODS AND SYSTEMS FOR IDENTIFYING PROTEINS CARNEGIE MELLON UNIVERSITY (US) 2002-10-31 WO claimed
WO-2002082088-A1 RECOVERY OF ENZYME ACTIVITY FROM ENVELOPED VIRUSES CAVIDI TECH AB (SE) 2002-10-17 WO claimed
US-20020137119-A1 Peptides representative of polypeptides of interest and antibodies directed thereagainst, and methods, systems and kits for generating and utilizing each KATZ EMIL ISRAEL (IL) 2002-09-26 US claimed
EP-1223534-A1 Peptides representative of polypeptides of interest and antibodies directed thereagainst, and methods, systems and kits for generating and utilizing each Katz, Emil (IL) 2002-07-17 EP claimed
US-6127150-A VECTOR FOR THE EFFICIENT EXPRESSION AND ISOLATION OF HETEROLOGOUS PROTEINS BIONEBRASKA, INC. (US) 2000-10-03 US claimed
US-5656456-A Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof BIONEBRASKA, INC. (US) 1997-08-12 US claimed
US-5635371-A Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof BIONEBRASKA, INC. (US) 1997-06-03 US claimed
US-5589364-A GENETIC ENGINEERING WITH PROTEINS FOR PROTEASE DEFICIENT MICROBIAL HOST TRANSFORMED WITH EXPRESSION VECTOR HAVING DNA CODES AND GENE EXPRESSION MAGAININ PHARMACEUTICALS INC. (US) 1996-12-31 US claimed
WO-1996017941-A2 PRODUCTION OF C-TERMINAL AMIDATED PEPTIDES FROM RECOMBINANT PROTEIN CONSTRUCTS BIONEBRASKA, INC. (US) 1996-06-13 WO claimed
WO-1996004373-A2 RECOMBINANT PRODUCTION OF BIOLOGICALLY ACTIVE PEPTIDES AND PROTEINS MAGAININ PHARMACEUTICALS, INC. (US) 1996-02-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577602-B2 Compositions and methods for peptide production LNPEP, CPN1, PRCP DTYMK 1889/4885TSHR 1047/4885CASP6 1073/4885
US-12570688-B2 Activated cysteine-directed polypeptide ligation technique PTMS, LNPEP, ANPEP DTYMK 2316/4885TSHR 973/4885CASP6 2041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.