Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807989 | 0.92 | TSPO (0.46) | TSPOHSD17B1HSD17B2RAB9AALDH1A1 | |
| SCHEMBL3807583 | 0.88 | NR1H4 (0.42) | HSD17B1HSD17B2RAB9ANPC1ALDH1A1 | |
| SCHEMBL3815202 | 0.88 | HSD17B1 (0.39) | TSPOHSD17B1HSD17B2MEN1KMT2A | |
| SCHEMBL3811131 | 0.87 | NR1H4 (0.49) | HSD17B1HSD17B2RAB9ANPC1ALDH1A1 | |
| SCHEMBL3811666 | 0.87 | MEN1 (0.41) | HSD17B1HSD17B2RAB9ANPC1ALDH1A1 | |
| SCHEMBL3807326 | 0.84 | KMT2A (0.39) | TSPOALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL3812648 | 0.84 | TSPO (0.46) | TSPOHSD17B1HSD17B2RAB9ANPC1 | |
| SCHEMBL3812096 | 0.83 | NR1H4 (0.43) | HSD17B1HSD17B2RAB9ANPC1ALDH1A1 | |
| SCHEMBL3809719 | 0.83 | KMT2A (0.39) | TSPORAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL3811519 | 0.82 | BACE1 (0.41) | TSPOALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |