Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807191 | 0.90 | PTGDR2 (0.48) | BACE1HDAC6MEN1KMT2APTGDR2 | |
| SCHEMBL3807989 | 0.89 | TSPO (0.46) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL3807457 | 0.89 | MLYCD (0.42) | BACE1MEN1KMT2APTGDR2MTOR | |
| SCHEMBL3814858 | 0.88 | LTB4R2 (0.44) | BACE1MEN1KMT2APTGDR2ALDH1A1 | |
| SCHEMBL3815298 | 0.88 | CPB1 (0.41) | BACE1HDAC6MEN1KMT2APTGDR2 | |
| SCHEMBL3811293 | 0.87 | LTB4R2 (0.40) | BACE1MEN1KMT2APTGDR2MTOR | |
| SCHEMBL3807190 | 0.86 | NR1H4 (0.42) | HDAC6SMN1; SMN2LMNA | |
| SCHEMBL3807326 | 0.86 | KMT2A (0.39) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL3807784 | 0.86 | NR1H4 (0.45) | SMN1; SMN2LMNA | |
| SCHEMBL3811516 | 0.85 | MTOR (0.41) | HDAC6MEN1KMT2APTGDR2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |